Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

25 questions · 25 findings · 1 reviews

No studies found 12 · 48%GRADE not reported 2 · 8%Very low 3 · 12%Low 7 · 28%Moderate 1 · 4%High 0 · 0%

PIMOZIDE vs antipsychotics

Adverse effects: extrapyramidal adverse effects Parkinsonism (tremor) medium term (< 3 months) Clinical diagnoses · patients with schizophrenia or related psychoses

PIMOZIDE showed no clear difference in adverse effects: extrapyramidal adverse effects Parkinsonism… compared with ANY ANTIPSYCHOTIC (low certainty).

1 finding from 1 review

PIMOZIDE vs antipsychotics

Quality of life: no significant change in quality of life/satisfaction medium term (3‐12 months) not reported · patients with schizophrenia or related psychoses

The review found no eligible studies for this question.

1 finding from 1 review

PIMOZIDE vs antipsychotics

Global state: relapse medium term (3‐12 months) Clinical diagnoses · patients with schizophrenia or related psychoses

PIMOZIDE showed no clear difference in global state: relapse medium term (3‐12 months) Clinical diagnoses compared with ANY ANTIPSYCHOTIC (moderate certainty).

1 finding from 1 review

PIMOZIDE vs antipsychotics

Mental state: no improvement medium term (3‐12 months) not reported · patients with schizophrenia or related psychoses

It is very uncertain whether PIMOZIDE changes mental state: no improvement medium term (3‐12 months) As defined in… compared with ANY ANTIPSYCHOTIC (very low certainty).

1 finding from 1 review