Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

25 questions · 25 findings · 1 reviews

No studies found 12 · 48%GRADE not reported 2 · 8%Very low 3 · 12%Low 7 · 28%Moderate 1 · 4%High 0 · 0%

PIMOZIDE + ANY ANTIPSYCHOTIC vs antipsychotics

Global state: relapse medium term (3‐12 months) Clinical diagnoses · patients with schizophrenia or related psychoses

PIMOZIDE + ANY ANTIPSYCHOTIC may leads to lower global state: relapsemedium term (3‐12 months) Clinical diagnoses compared with ANY ANTIPSYCHOTIC (low certainty).

1 finding from 1 review

PIMOZIDE + ANY ANTIPSYCHOTIC vs placebo/no adjunctive treatment + antipsychotics

Global state: relapse medium term (3‐12 months) Clinical diagnoses · patients with schizophrenia or related psychoses

PIMOZIDE + ANY ANTIPSYCHOTIC showed no clear difference in global state: relapse medium term (3‐12 months) compared with ANTIPSYCHOTIC + PLACEBO; GRADE not reported.

1 finding from 1 review

PIMOZIDE vs antipsychotics

Mental state: presence of first‐rank symptoms medium term (3‐12 months) Clinical diagnoses · patients with schizophrenia or related psychoses

PIMOZIDE showed no clear difference in mental state: presence of first‐rank symptoms medium term (3‐12… compared with ANY ANTIPSYCHOTIC (low certainty).

1 finding from 1 review

PIMOZIDE vs antipsychotics

Adverse effects: extrapyramidal adverse effectsParkinsonism (rigidity) short term (< 3 months) Clinical diagnoses · patients with schizophrenia or related psychoses

PIMOZIDE showed no clear difference in adverse effects: extrapyramidal adverse effectsParkinsonism… compared with ANY ANTIPSYCHOTIC (low certainty).

1 finding from 1 review