Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

230 questions · 243 findings · 23 reviews · Headline outcomes only

No studies found 52 · 21.4%GRADE not reported 10 · 4.1%Very low 85 · 35%Low 51 · 21%Moderate 37 · 15.2%High 8 · 3.3%

Subgroup analyses: early vs standard initiation of kidney replacement therapy (KRT)

Death by AKI aetiology: non‐surgical causes · AKI

Subgroup analyses: early showed no clear difference in death by AKI aetiology: non‐surgical causes compared with standard initiation of kidney replacement therapy (KRT) (moderate certainty).

1 finding from 1 review

Intervention not reported

Perioperative bleeding requiring non‐surgical intervention · patients with paediatric tonsillectomy

The intervention showed no clear difference in perioperative bleeding requiring non‐surgical intervention (moderate certainty).

1 finding from 1 review

Surgical vs non‐surgical treatment

Number of participants sustaining recurrent patellar dislocation · people with lateral patellar dislocation

It is very uncertain whether surgical changes number of participants sustaining recurrent patellar dislocationa compared with non‐surgical treatment (very low certainty).

1 finding from 1 review

Surgical vs non‐surgical treatment

Kujala patellofemoral disorders score Scale from: 0 to 100 (higher scores = better function) · people with lateral patellar dislocation

It is very uncertain whether surgical changes knee and physical functiona Measured using the Kujala patellofemoral… compared with non‐surgical treatment (very low certainty).

1 finding from 1 review

Surgical vs non‐surgical treatment

Adverse effects of treatment Overall incidence of complications · people with lateral patellar dislocation

It is very uncertain whether surgical changes adverse effects of treatment Overall incidence of complications compared with non‐surgical treatment (very low certainty).

1 finding from 1 review

Surgical vs non‐surgical treatment

Patient‐reported knee instabilitya Incidence of patellar subluxation · people with lateral patellar dislocation

It is very uncertain whether surgical changes patient‐reported knee instabilitya Incidence of patellar subluxation compared with non‐surgical treatment (very low certainty).

1 finding from 1 review

Surgical vs non‐surgical treatment

Subsequent requirement for surgery (re‐operations) for complications Incidence · people with lateral patellar dislocation

It is very uncertain whether surgical changes subsequent requirement for surgery (reoperations) for complicationsa… compared with non‐surgical treatment (very low certainty).

1 finding from 1 review

Surgical vs non‐surgical treatment

Complications requiring unplanned return to theatre Subtalar arthrodesis · people aged over 14 years with displaced intra‐articular calcaneal fractures

Surgical showed no clear difference in complications requiring unplanned return to theatre Subtalar… compared with non‐surgical management (low certainty).

1 finding from 1 review