evidencegaps
Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

36 questions · 36 findings · 13 reviews · Headline outcomes only

Sort:Best matchNewestHighest certaintyDownload CSV
No studies found 11 · 30.6%GRADE not reported 1 · 2.8%Very low 6 · 16.7%Low 11 · 30.6%Moderate 6 · 16.7%High 1 · 2.8%

MHRV vs placebo

Change in Morning PEF after 12 months (% predicted) · asthmatics with sensitivity to house dust mite

MHRV showed no clear difference in change in Morning PEF after 12 months (% predicted) compared with placebo (moderate certainty).

1 finding from 1 review

Evening vs morning dosing regimen

All‐cause mortality · adults with primary (essential) hypertension whose systolic or diastolic (or both) blood pressure levels were 130/80 mmHg or greater

It is very uncertain whether evening changes all‐cause mortality compared with morning dosing regimen (very low certainty).

1 finding from 1 review

Evening vs morning dosing regimen

Serious adverse events · adults with primary (essential) hypertension whose systolic or diastolic (or both) blood pressure levels were 130/80 mmHg or greater

It is very uncertain whether evening changes serious adverse events compared with morning dosing regimen (very low certainty).

1 finding from 1 review

Evening vs morning dosing regimen

Overall adverse events · adults with primary (essential) hypertension whose systolic or diastolic (or both) blood pressure levels were 130/80 mmHg or greater

It is very uncertain whether evening changes overall adverse events compared with morning dosing regimen (very low certainty).

1 finding from 1 review

Evening vs morning dosing regimen

Withdrawals due to adverse events · adults with primary (essential) hypertension whose systolic or diastolic (or both) blood pressure levels were 130/80 mmHg or greater

It is very uncertain whether evening changes withdrawals from treatment due to adverse events compared with morning dosing regimen (very low certainty).

1 finding from 1 review

Summary of findings: Evening RT vs morning RT

Acute and late GI toxicity (grade 2+) · People undergoing radiotherapy for uterine cervical cancer

Summary of findings: Evening RT may leads to lower acute and late GI toxicity (grade 2+) compared with morning RT (low certainty).

1 finding from 1 review