Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

93 questions · 95 findings · 8 reviews · Pregnancy and Childbirth

No studies found 44 · 46.3%GRADE not reported 10 · 10.5%Very low 22 · 23.2%Low 12 · 12.6%Moderate 7 · 7.4%High 0 · 0%

Summary of findings: Low‐moderate GI diet vs moderate‐high GI diet (maternal outcomes)

Eclampsia · pregnant women with GDM

It is very uncertain whether summary of findings: Low‐moderate GI diet changes hypertensive disorders of pregnancy: eclampsia compared with moderate‐high GI diet (maternal outcomes) (very low certainty).

1 finding from 1 review

Summary of findings: Low‐moderate GI diet vs moderate‐high GI diet (neonatal/child/adulthood outcomes)

Large‐for‐gestational age · pregnant women with GDM

Summary of findings: Low‐moderate GI diet showed no clear difference in large‐for‐gestational age compared with moderate‐high GI diet (neonatal/child/adulthood outcomes) (low certainty).

1 finding from 1 review

Dexamethasone vs betamethasone – child outcomes

Developmental delay –motor (mild, moderate or severe) · women at risk of preterm birth

Dexamethasone showed no clear difference in developmental delay –motor (mild, moderate or severe) compared with betamethasone – child outcomes (moderate certainty).

1 finding from 1 review

Dexamethasone vs betamethasone – child outcomes

Intellectual impairment: developmental delay – cognitive or language (mild, moderate or severe) · women at risk of preterm birth

Dexamethasone showed no clear difference in intellectual impairment: developmental delay – cognitive or language… compared with betamethasone – child outcomes (moderate certainty).

1 finding from 1 review

Cooling treatment (ice pack) vs no treatment

Perineal pain within 24 hours of giving birth ‐ Moderate + severe pain · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth

It is very uncertain whether cooling treatment (ice pack or cold gel pad) changes perineal pain within 24 hours of giving birth ‐ Moderate + severe pain compared with no treatment (very low certainty).

1 finding from 1 review

Cooling treatment (ice pack) vs cooling treatment (cold gel pad)

Perineal pain within 4 ‐ 6 hours of giving birth ‐ Moderate + severe pain · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth

It is very uncertain whether cooling treatment (ice pack) changes perineal pain within 4 ‐ 6 hours of giving birth ‐ Moderate + severe… compared with cooling treatment (cold gel pad) (very low certainty).

1 finding from 1 review

Cooling treatment (ice pack) vs cooling treatment (cold gel pad)

Perineal pain within 24 hours of giving birth ‐ Moderate + severe pain · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth

It is very uncertain whether cooling treatment (ice pack) changes perineal pain within 24 hours of giving birth ‐ Moderate + severe pain compared with cooling treatment (cold gel pad) (very low certainty).

1 finding from 1 review

Cooling treatment (ice pack) vs cooling treatment (cold gel pad)

Perineal pain 24 ‐ 48 hours after giving birth ‐ Moderate + severe pain · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth

It is very uncertain whether cooling treatment (ice pack) changes perineal pain 24 ‐ 48 hours after giving birth ‐ Moderate + severe… compared with cooling treatment (cold gel pad) (very low certainty).

1 finding from 1 review

Cooling treatment (ice pack) vs no treatment

Perineal pain 24 ‐ 48 hours after giving birth ‐ Moderate + severe pain · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth

It is very uncertain whether cooling treatment (ice pack or cold gel pad) changes perineal pain between 24 ‐ 48 after giving birth ‐ Moderate + severe… compared with no treatment (very low certainty).

1 finding from 1 review

Intervention not reported

Maternal pain score or pain measured in labour (Pain intensity at 1 hour (moderate or severe))
1 finding from 1 review

Selective vs routine episiotomy: all vaginal births where operative vaginal delivery was not anticipated

Women with moderate or severe pain (measured by visual analogue scale) · Women in labour where operative delivery was not anticipated. (Women were above 16 years old and between 28 gestational weeks and full…

It is very uncertain whether selective changes women with moderate or severe pain (measured by visual analogue scale) compared with routine episiotomy: all vaginal births where operative vaginal… (very low certainty).

1 finding from 1 review

Any antihypertensive drug vs no antihypertensive drugs/placebo

Maternal · women with mild to moderate hypertension during pregnancy

The review found no eligible studies for this question.

2 findings from 1 review