Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

145 questions · 151 findings · 8 reviews · Kidney and Transplant

No studies found 21 · 13.9%GRADE not reported 2 · 1.3%Very low 26 · 17.2%Low 73 · 48.3%Moderate 23 · 15.2%High 6 · 4%

Calcineurin inhibitor vs IV cyclophosphamide

Discontinuation of medication due to adverse events · idiopathic steroid‐resistant nephrotic syndrome in children

Calcineurin inhibitor probably leads to lower adverse events: medications ceased due to adverse events compared with IV cyclophosphamide (moderate certainty).

1 finding from 1 review