Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

43 questions · 43 findings · 5 reviews · Pregnancy and Childbirth

No studies found 10 · 23.3%GRADE not reported 4 · 9.3%Very low 6 · 14%Low 19 · 44.2%Moderate 4 · 9.3%High 0 · 0%

Vaginal misoprostol vs placebo

Opiate use (as a proxy measure for pain) for all participants on ITT (including those without confirmed AMI) · early fetal death (less than 24 weeks)

It is very uncertain whether vaginal misoprostol changes pain (opiate use) compared with placebo (very low certainty).

1 finding from 1 review

Misoprostol vs surgery

Unplanned surgical intervention · incomplete miscarriage

Misoprostol may leads to higher unplanned surgical intervention compared with surgery (low certainty).

1 finding from 1 review

Misoprostol vs surgery

Women's views/acceptability of method · incomplete miscarriage

Misoprostol showed no clear difference in women's views/acceptability of method compared with surgery (moderate certainty).

1 finding from 1 review