Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

101 questions · 119 findings · 11 reviews · Gynaecology and Fertility

No studies found 18 · 15.1%GRADE not reported 0 · 0%Very low 41 · 34.5%Low 36 · 30.3%Moderate 21 · 17.6%High 3 · 2.5%

LOD with and without medical ovulation vs medical ovulation induction alone

Clincial pregnancy · women with anovulatory PCOS and CC resistance

LOD with and without medical ovulation showed no clear difference in clincial pregnancy compared with medical ovulation induction alone (low certainty).

1 finding from 1 review

LOD with and without medical ovulation vs medical ovulation induction alone

Miscarriage · women with anovulatory PCOS and CC resistance

LOD with and without medical ovulation showed no clear difference in miscarriage compared with medical ovulation induction alone (low certainty).

1 finding from 1 review

Medical treatment vs placebo

Improvement in pain score (up to nine months after treatment): progesterone versus placebo · women with chronic pelvic pain

Medical treatment probably leads to higher improvement in pain score at end of treatment: progesterone versus… compared with placebo (moderate certainty).

2 findings from 1 review

Antioestrogen plus medical adjunct vs antioestrogen

Clinical pregnancy · ovulation induction in polycystic ovarian syndrome

Antioestrogen plus medical adjunct showed no clear difference in clomiphene citrate plus bromocriptine versus clomiphene citrate ‐… compared with antioestrogen alone (low certainty).

1 finding from 1 review

GnRHa treatment vs other medical therapies before any surgery

Preoperative bleeding: (PBAC < 75) ulipristal acetate 5 mg · women with uterine fibroids

GnRHa treatment showed no clear difference in preoperative bleeding: Reduction in bleeding to PBAC < 75 ulipristal… compared with other medical therapies before any surgery (moderate certainty).

1 finding from 1 review

GnRHa treatment vs other medical therapies before any surgery

Preoperative bleeding: Reduction in bleeding to PBAC < 75 ulipristal acetate 10 mg · women with uterine fibroids

GnRHa treatment showed no clear difference in preoperative bleeding: Reduction in bleeding to PBAC < 75 ulipristal… compared with other medical therapies before any surgery (moderate certainty).

1 finding from 1 review