Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

97 questions · 100 findings · 5 reviews · Pregnancy and Childbirth

No studies found 33 · 33%GRADE not reported 0 · 0%Very low 34 · 34%Low 24 · 24%Moderate 7 · 7%High 2 · 2%

Oral magnesium vs placebo/no treatment

Frequency of leg cramps after treatment: never · treating leg cramps in pregnancy

Oral magnesium may leads to higher frequency of leg cramps after treatment: never compared with placebo/no treatment (low certainty).

1 finding from 1 review

Oral magnesium vs placebo/no treatment

Frequency: 50% reduction in number of leg cramps · treating leg cramps in pregnancy

Oral magnesium may leads to higher frequency: 50% reduction in number of leg cramps compared with placebo/no treatment (low certainty).

1 finding from 1 review

Oral magnesium vs placebo/no treatment

Intensity of pain during treatment: mean total scale points The degree of pain was noted in the form, on a scale from 0 to 4 measured over 4 days and nights (0 = no pain, 1 = light pain, 2 = medium pain, 3=strong pain, 4=extreme pain) · treating leg cramps in pregnancy
1 finding from 1 review

Oral magnesium vs placebo/no treatment

At least 50% reduction in pain · treating leg cramps in pregnancy

It is very uncertain whether oral magnesium changes intensity of pain: 50% reduction in pain score 100‐mm visual… compared with placebo/no treatment (very low certainty).

1 finding from 1 review

Oral magnesium vs placebo/no treatment

Duration of leg cramps: persisting symptoms after night‐time cramps Always · treating leg cramps in pregnancy

Oral magnesium may leads to lower duration of leg cramps: persisting symptoms after night‐time cramps… compared with placebo/no treatment (low certainty).

1 finding from 1 review

Oral magnesium vs placebo/no treatment

Duration of leg cramps: persisting symptoms after night‐time cramps Sometimes · treating leg cramps in pregnancy

It is very uncertain whether oral magnesium changes duration of leg cramps: persisting symptoms after night‐time cramps… compared with placebo/no treatment (very low certainty).

1 finding from 1 review

Oral magnesium vs placebo/no treatment

Composite outcome: symptoms of leg cramps (intensity and frequency) Partial improvement: decrease in intensity and frequency · treating leg cramps in pregnancy

It is very uncertain whether oral magnesium changes composite outcome: symptoms of leg cramps (intensity and frequency)… compared with placebo/no treatment (very low certainty).

1 finding from 1 review

Summary of findings for subcutaneous terbutaline vs IV magnesium sulphate

Low umbilical artery pH (< 7.2 or as defined by trial authors) · women for whom a decision had been made to deliver by caesarean section for suspected fetal distress based on FHR monitoring

It is very uncertain whether summary of findings for subcutaneous terbutaline changes umbilical artery pH < 7.2 compared with IV magnesium sulphate (very low certainty).

1 finding from 1 review

Summary of findings for subcutaneous terbutaline vs IV magnesium sulphate

Resolution of fetal distress on FHR tracing · women for whom a decision had been made to deliver by caesarean section for suspected fetal distress based on FHR monitoring

It is very uncertain whether summary of findings for subcutaneous terbutaline changes resolution of fetal distress on FHR tracing compared with IV magnesium sulphate (very low certainty).

1 finding from 1 review

Treatment of eclampsia: loading dose alone vs loading dose + maintenance regimen

Recurrence of convulsions · women with eclampsia

It is very uncertain whether treatment of eclampsia: loading dose alone changes recurrence of convulsion compared with loading dose plus maintenance dose regimen (very low certainty).

1 finding from 1 review

Treatment of eclampsia: lower‐dose regimens vs standard‐dose strategies

Death of the baby before discharge: perinatal death · women with eclampsia

It is very uncertain whether treatment of eclampsia: lower‐dose regimens changes death of the baby before discharge: perinatal death: lower dose… compared with standard‐dose regimens (very low certainty).

1 finding from 1 review