Major disability by 18 to 24 months corrected age (aligned definition) · women at risk of preterm birth (< 34 weeks' gestation)
Magnesium sulphate showed no clear difference in major neurodevelopmental disability (up to 2 years' corrected age)** compared with placebo (outcomes (moderate certainty).
1 finding from 1 review
Intraventricular haemorrhage, Papile grade 3/4 · women at risk of preterm birth (< 34 weeks' gestation)
Magnesium sulphate probably leads to lower severe intraventricular haemorrhage (grade 3 or 4) (newborn/infant)** compared with placebo (outcomes (moderate certainty).
1 finding from 1 review
Bronchopulmonary dysplasia/chronic lung disease · women at risk of preterm birth (< 34 weeks' gestation)
Magnesium sulphate showed no clear difference in chronic lung disease/bronchopulmonary dysplasia (newborn/infant)** compared with placebo (outcomes (low certainty).
1 finding from 1 review
Death (fetal, neonatal, or later (up to school age))** · women at risk of preterm birth (< 34 weeks' gestation)
Magnesium sulphate showed no clear difference in death (fetal, neonatal, or later (up to school age))** compared with placebo (outcomes (low certainty).
1 finding from 1 review
Time to recovery · children up to 18 months old with acute bronchiolitis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events · children up to 12 months old with acute bronchiolitis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Length of hospital stay · children up to 12 months old with acute bronchiolitis
It is very uncertain whether magnesium sulphate changes duration of hospital stay compared with hypertonic saline (very low certainty).
1 finding from 1 review
Clinical severity score (CSS) (RDAI score; range 0 to 17; higher = poorer outcomes) measured at 0 to 24 hoursafter treatment · children up to 12 months old with acute bronchiolitis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Clinical severity score (CSS) (RDAI score; range 0 to 17; higher = poorer outcomes) measured 25 to 48 hoursafter treatment · children up to 12 months old with acute bronchiolitis
It is very uncertain whether magnesium sulphate changes clinical severity score (CSS) (RDAI score; range 0 to 17; higher =… compared with hypertonic saline (very low certainty).
1 finding from 1 review
Hospital re‐admission within 30 days of discharge · children up to 12 months old with acute bronchiolitis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
All‐cause mortality · children up to 18 months old with acute bronchiolitis
1 finding from 1 review
Adverse events · children up to 18 months old with acute bronchiolitis
1 finding from 1 review
Length of hospital stay · children up to 18 months old with acute bronchiolitis
1 finding from 1 review
Clinical severity score (CSS) (Wang score; range 0 to 12; higher = poorer outcome) measured at 0 to 24 hoursafter treatment · children up to 18 months old with acute bronchiolitis
It is very uncertain whether magnesium sulphate changes clinical severity score (CSS) (Wang score; range 0 to 12; higher =… compared with placebo (very low certainty).
1 finding from 1 review
Clinical severity score (CSS) (Wang score; range 0 to 12; higher = poorer outcome) measured 25 to 48 hoursafter treatment · children up to 18 months old with acute bronchiolitis
It is very uncertain whether magnesium sulphate changes clinical severity score (CSS) (Wang score; range 0 to 12; higher =… compared with placebo (very low certainty).
1 finding from 1 review
Hospital re‐admission within 30 days of discharge · children up to 18 months old with acute bronchiolitis
Magnesium sulphate may leads to higher hospital re‐admission within 30 days of discharge (re‐admissions… compared with placebo (low certainty).
1 finding from 1 review
Time to recovery · children up to 12 months old with acute bronchiolitis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
All‐cause mortality · children up to 12 months old with acute bronchiolitis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Frequency of leg cramps during treatment · treating leg cramps in pregnancy
1 finding from 1 review
Composite outcome: symptoms of leg cramps (intensity and frequency) Complete recovery: no leg cramps after treatment · treating leg cramps in pregnancy
It is very uncertain whether oral magnesium changes composite outcome: symptoms of leg cramps (intensity and frequency)… compared with placebo/no treatment (very low certainty).
1 finding from 1 review