Findings

What do systematic reviews say?

30 questions · 30 findings · 6 reviews · Pain, Palliative and Supportive Care

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No studies found 11 · 36.7%GRADE not reported 0 · 0%Very low 4 · 13.3%Low 15 · 50%Moderate 0 · 0%High 0 · 0%

Topical clonidine (TC) vs active comparators

Participant‐reported pain relief of 50% or greater · adults with painful diabetic neuropathy

Topical clonidine (TC) showed no clear difference in participant‐reported pain relief of 50% or greater during longest compared with active comparator (low certainty).

1 finding from 1 review

Topical clonidine for neuropathic pain in adults 2022 · Cochrane Headline outcomes only
RR 1.41 [0.99, 2]
1 study · 139 participants
Low

Topical clonidine (TC) vs active comparators

Participant‐reported pain relief of 30% or greater · adults with painful diabetic neuropathy

The review found no eligible studies for this question.

1 finding from 1 review

Topical clonidine for neuropathic pain in adults 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Aromatherapy massage vs no massage

Symptoms relating to the breast (EORTC QLQ‐BR23): long‐term (≥ 8 weeks) · cancer patients

1 finding from 1 review

Massage with or without aromatherapy for symptom relief in people with cancer 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 86 participants
Very low

Aromatherapy massage vs no massage

Bodily pain (SF‐8) ‐ long‐term (≥ 8 weeks) · cancer patients

1 finding from 1 review

Massage with or without aromatherapy for symptom relief in people with cancer 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 86 participants
Very low

High‐dose corticosteroids vs moderate‐dose or no corticosteroids

Survival (long term) Over two years · adults with metastatic extradural spinal cord compression (without peptic ulceration or infection; mixed prognosis)

High‐dose corticosteroids showed no clear difference in survival (long term) Over two years compared with moderate‐dose or no corticosteroids (low certainty).

1 finding from 1 review

Interventions for the treatment of metastatic extradural spinal cord compression in adults 2015 · Cochrane Headline outcomes only
RR 1.11 [0.24, 5.05]
1 study · 57 participants
Low

Intervention not reported

Change in long‐term QoL CARES‐SF (global) · 106 participants with primary brain tumour

1 finding from 1 review

Multidisciplinary rehabilitation after primary brain tumour treatment 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 106 participants
Low

Intervention not reported

Change in long‐term disability (function) FIM motor · 106 participants with primary brain tumour

1 finding from 1 review

Multidisciplinary rehabilitation after primary brain tumour treatment 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 106 participants
Low

Intervention not reported

Change in long‐term disability (cognition) FIM cognition · 106 participants with primary brain tumour

1 finding from 1 review

Multidisciplinary rehabilitation after primary brain tumour treatment 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 106 participants
Low

Intervention not reported

Change in long‐term psychological outcomes DASS (total) · 106 participants with primary brain tumour

1 finding from 1 review

Multidisciplinary rehabilitation after primary brain tumour treatment 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 106 participants
Low

Intervention not reported

Change in long‐term participation PIPP (total) · 106 participants with primary brain tumour

1 finding from 1 review

Multidisciplinary rehabilitation after primary brain tumour treatment 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 106 participants
Low