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Evidence found and GRADE certainty

249 questions · 255 findings · 18 reviews · Headline outcomes only

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No studies found 68 · 26.7%GRADE not reported 5 · 2%Very low 102 · 40%Low 44 · 17.3%Moderate 32 · 12.5%High 4 · 1.6%

Laser therapy plus other treatment vs other treatment

Incidence of treatment‐related adverse effects ‐ CO2 laser plus TAC versus cryosurgery plus TAC ‐ hypopigmentation ‐ keloid scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy plus other treatment changes incidence of treatment‐related adverse effects ‐ CO2 laser plus TAC… compared with other treatment (very low certainty).

1 finding from 1 review

Laser therapy plus other treatment vs other treatment

Scar severity ‐ Neodymium‐doped yttrium aluminium garnet (Nd:YAG) laser plus Diprospan plus 5‐FU versus Diprospan plus 5‐FU ‐ blinded observer assessment of good to excellent scar improvement ‐ keloid scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy plus other treatment changes scar severity ‐ Neodymium‐doped yttrium aluminium garnet (Nd:YAG)… compared with other treatment (very low certainty).

1 finding from 1 review

Laser therapy plus other treatment vs other treatment

Scar severity: Nd:YAG laser plus Diprospan plus 5‐FU versus Diprospan plus 5‐FU ‐ patient self‐assessment of scar improvement of 50% or higher ‐ keloid scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy plus other treatment changes scar severity: Nd:YAG laser plus Diprospan plus 5‐FU versus… compared with other treatment (very low certainty).

1 finding from 1 review

Laser therapy plus other treatment vs other treatment

Scar severity ‐ Helium‐Neon (He‐Ne) laser plus decamethyltetrasiloxane, polydimethylsiloxane and cyclopentasiloxane cream versus decamethyltetrasiloxane, polydimethylsiloxane and cyclopentasiloxane cream ‐ Vancouver Scar scale (VSS) (higher scores... · participants with hypertrophic and keloid scars
1 finding from 1 review

Laser therapy vs other treatments

Scar severity ‐ 585‐nm PDL versus TAC ‐ patient self‐assessment of scar improvement of 50% or higher, or patients considering the scar better or much better ‐ hypertrophic and keloid scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy changes scar severity ‐ 585‐nm PDL versus TAC ‐ patient self‐assessment of… compared with other treatments (very low certainty).

1 finding from 1 review

Laser therapy vs other treatments

Incidence and severity of treatment‐related adverse effects ‐ 585‐nm PDL versus TAC: sequelae ‐ hypertrophic and keloid scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy changes incidence and severity of treatment‐related adverse effects ‐ 585‐nm… compared with other treatments (very low certainty).

1 finding from 1 review

Laser therapy vs other treatments

Incidence and severity of treatment‐related adverse effects ‐ 585‐nm PDL versus TAC ‐ mild to moderate pain related to treatment ‐ hypertrophic and keloid scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy changes incidence and severity of treatment‐related adverse effects ‐ 585‐nm… compared with other treatments (very low certainty).

1 finding from 1 review

Laser therapy vs other treatments

Scar severity ‐ 585‐nm PDL versus 5‐FU ‐ patient self‐assessment of scar improvement of 50% or higher ‐ hypertrophic and keloid scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy changes scar severity ‐ 585‐nm PDL versus 5‐FU ‐ patient self‐assessment of… compared with other treatments (very low certainty).

1 finding from 1 review

Laser therapy vs other treatments

Incidence and severity of treatment‐related adverse effects ‐ 585‐nm PDL versus 5‐FU ‐ mild to moderate pain related to treatment ‐ hypertrophic and keloid scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy changes incidence and severity of treatment‐related adverse effects ‐ 585‐nm… compared with other treatments (very low certainty).

1 finding from 1 review

Laser therapy vs other treatments

Incidence and severity of treatment‐related adverse effects ‐ 585‐nm PDL versus 5‐FU ‐ purpura ‐ hypertrophic and keloid scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy changes incidence and severity of treatment‐related adverse effects ‐ 585‐nm… compared with other treatments (very low certainty).

1 finding from 1 review

Laser therapy vs other treatments

Scar severity ‐ 585‐nm PDL versus TAC plus 5‐FU ‐ patient self‐assessment of scar improvement of 50% or higher ‐ hypertrophic and keloid scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy changes scar severity ‐ 585‐nm PDL versus TAC plus 5‐FU ‐ patient… compared with other treatments (very low certainty).

1 finding from 1 review

Laser therapy vs no treatment

Incidence and severity of treatment‐related adverse effects ‐ 585‐nm PDL versus no treatment ‐ mild to moderate discomfort or pain related to treatment ‐ hypertrophic and keloid scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy changes incidence and severity of treatment‐related adverse effects ‐ 585‐nm… compared with no treatment (very low certainty).

1 finding from 1 review

Laser therapy vs other treatments

Incidence and severity of treatment‐related adverse effects ‐ 585‐nm PDL versus TAC plus 5‐FU ‐ mild to moderate pain related to treatment ‐ hypertrophic and keloid scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy changes incidence and severity of treatment‐related adverse effects ‐ 585‐nm… compared with other treatments (very low certainty).

1 finding from 1 review