What do systematic reviews say?

Summary of findings table: photocoagulation of drusen vs control

• Laser treatment of drusen to prevent progression to advanced age‐related macular degeneration 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 44 participants
  Low

Summary of findings table: photocoagulation of drusen vs control

Summary of findings table: photocoagulation of drusen leads to higher drusen reduction compared with control (high certainty).

• Laser treatment of drusen to prevent progression to advanced age‐related macular degeneration 2015 · Cochrane Headline outcomes only
  OR 9.16 [6.28, 13.4]
  3 studies · 570 participants
  High

Subthreshold vs standard macular photocoagulation

• Monotherapy laser photocoagulation for diabetic macular oedema 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Low

Subthreshold vs standard macular photocoagulation

Subthreshold showed no clear difference in anatomic measures: partial to complete resolution of the macular… compared with standard macular photocoagulation (low certainty).

• Monotherapy laser photocoagulation for diabetic macular oedema 2018 · Cochrane Headline outcomes only
  RR 0.47 [0.21, 1.03]
  Studies not reported
  Low

Subthreshold vs standard macular photocoagulation

• Monotherapy laser photocoagulation for diabetic macular oedema 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Moderate

Subthreshold vs standard macular photocoagulation

The review found no eligible studies for this question.

• Monotherapy laser photocoagulation for diabetic macular oedema 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Subthreshold vs standard macular photocoagulation

The review found no eligible studies for this question.

• Monotherapy laser photocoagulation for diabetic macular oedema 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Subthreshold vs standard macular photocoagulation

It is very uncertain whether subthreshold changes improvement of BCVA defined as ≥ 15 ETDRS letters (i.e. 3 ETDRS… compared with standard macular photocoagulation (very low certainty).

• Monotherapy laser photocoagulation for diabetic macular oedema 2018 · Cochrane Headline outcomes only
  RR 0.31 [0.01, 7.09]
  Studies not reported
  Very low

Subthreshold vs standard macular photocoagulation

It is very uncertain whether subthreshold changes worsening of BCVA defined as ≥ 15 ETDRS letters (i.e. 3 ETDRS lines… compared with standard macular photocoagulation (very low certainty).

• Monotherapy laser photocoagulation for diabetic macular oedema 2018 · Cochrane Headline outcomes only
  RR 0.93 [0.15, 5.76]
  Studies not reported
  Very low