Findings

What do systematic reviews say?

32 questions · 37 findings · 3 reviews

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No studies found 2 · 5.4%GRADE not reported 5 · 13.5%Very low 8 · 21.6%Low 12 · 32.4%Moderate 10 · 27%High 0 · 0%

Endovenous laser ablation (EVLA) vs SFJ ligation and stripping (HL/S)

Recurrence · people with GSV incompetence

Endovenous laser ablation (EVLA) showed no clear difference in recurrence (< 5 years) compared with SFJ ligation and stripping (HL/S) (moderate certainty).

1 finding from 1 review

Interventions for great saphenous vein incompetence 2021 · Cochrane Headline outcomes only
OR 0.78 [0.47, 1.29]
7 studies · 1459 participants
Moderate

Endovenous laser ablation (EVLA) vs SFJ ligation and stripping (HL/S)

Long‐term recurrence (> 5 years) · people with GSV incompetence

Endovenous laser ablation (EVLA) showed no clear difference in long‐term recurrence (> 5 years) compared with SFJ ligation and stripping (HL/S) (moderate certainty).

1 finding from 1 review

Interventions for great saphenous vein incompetence 2021 · Cochrane Headline outcomes only
OR 1.09 [0.68, 1.76]
7 studies · 1267 participants
Moderate

Endovenous laser ablation (EVLA) vs SFJ ligation and stripping (HL/S)

Complications (up to 8 years) · people with GSV incompetence

1 finding from 1 review

Interventions for great saphenous vein incompetence 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Endovenous laser ablation (EVLA) vs SFJ ligation and stripping (HL/S)

QoL · people with GSV incompetence

1 finding from 1 review

Interventions for great saphenous vein incompetence 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Moderate

Endovenous laser ablation (EVLA) vs foam sclerotherapy

Technical success · people with GSV incompetence

Endovenous laser ablation (EVLA) showed no clear difference in technical success (< 5 years) compared with ultrasound‐guided foam sclerotherapy (UGFS) (low certainty).

2 findings from 1 review

Interventions for great saphenous vein incompetence 2021 · Cochrane Headline outcomes only
OR 6.13 [0.98, 38.27]
3 studies · 588 participants
Low
Interventions for great saphenous vein incompetence 2021 · Cochrane Headline outcomes only
OR 6.47 [2.6, 16.1]
3 studies · 534 participants
Low

Endovenous laser ablation (EVLA) vs foam sclerotherapy

Recurrence · people with GSV incompetence

It is very uncertain whether endovenous laser ablation (EVLA) changes recurrence (< 5 years) compared with ultrasound‐guided foam sclerotherapy (UGFS) (very low certainty).

1 finding from 1 review

Interventions for great saphenous vein incompetence 2021 · Cochrane Headline outcomes only
OR 0.68 [0.2, 2.36]
2 studies · 443 participants
Very low

Ultrasound‐guided foam sclerotherapy vs conventional surgery

Recurrence · people requiring intervention for short saphenous vein varices

1 finding from 1 review

Endovenous ablation therapy (laser or radiofrequency) or foam sclerotherapy versus conventional surgical repair for… 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 31 participants
GRADE not reported

Ultrasound‐guided foam sclerotherapy vs conventional surgery

Reintervention (due to technical failure) · people requiring intervention for short saphenous vein varices

1 finding from 1 review

Endovenous ablation therapy (laser or radiofrequency) or foam sclerotherapy versus conventional surgical repair for… 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 31 participants
GRADE not reported

Ultrasound‐guided foam sclerotherapy vs conventional surgery

Disease‐specific quality of life · people requiring intervention for short saphenous vein varices

2 findings from 1 review

Endovenous ablation therapy (laser or radiofrequency) or foam sclerotherapy versus conventional surgical repair for… 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 33 participants
GRADE not reported
Endovenous ablation therapy (laser or radiofrequency) or foam sclerotherapy versus conventional surgical repair for… 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 31 participants
GRADE not reported

Ultrasound‐guided foam sclerotherapy vs conventional surgery

Complications at 1 year · people requiring intervention for short saphenous vein varices

1 finding from 1 review

Endovenous ablation therapy (laser or radiofrequency) or foam sclerotherapy versus conventional surgical repair for… 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 31 participants
GRADE not reported

Ultrasound‐guided foam sclerotherapy vs conventional surgery

Recanalisation or persistence of reflux at 6 weeks · people requiring intervention for short saphenous vein varices

Ultrasound‐guided foam sclerotherapy showed no clear difference in recanalisation or persistence of reflux at 6 weeks compared with conventional surgery (low certainty).

1 finding from 1 review

Endovenous ablation therapy (laser or radiofrequency) or foam sclerotherapy versus conventional surgical repair for… 2016 · Cochrane Headline outcomes only
OR 0.34 [0.06, 2.1]
1 study · 33 participants
Low

Ultrasound‐guided foam sclerotherapy vs conventional surgery

Recurrence of reflux at 1 year · people requiring intervention for short saphenous vein varices

Ultrasound‐guided foam sclerotherapy showed no clear difference in recurrence of reflux at 1 year compared with conventional surgery (low certainty).

1 finding from 1 review

Endovenous ablation therapy (laser or radiofrequency) or foam sclerotherapy versus conventional surgical repair for… 2016 · Cochrane Headline outcomes only
OR 1.19 [0.29, 4.92]
1 study · 31 participants
Low