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What do systematic reviews say?

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Evidence found and GRADE certainty

26 questions · 26 findings · 3 reviews

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No studies found 2 · 7.7%GRADE not reported 0 · 0%Very low 12 · 46.2%Low 8 · 30.8%Moderate 4 · 15.4%High 0 · 0%

Non‐absorbable disaccharides vs placebo or no intervention

All‐cause mortality · prevention and treatment of hepatic encephalopathy in people with cirrhosis

Non‐absorbable disaccharides probably leads to lower mortality compared with placebo/no intervention (moderate certainty).

1 finding from 1 review

Non‐absorbable disaccharides vs placebo or no intervention

Hepatic encephalopathy · prevention and treatment of hepatic encephalopathy in people with cirrhosis

Non‐absorbable disaccharides probably leads to lower hepatic encephalopathy compared with placebo/no intervention (moderate certainty).

1 finding from 1 review

Non‐absorbable disaccharides vs placebo or no intervention

Serious adverse events · prevention and treatment of hepatic encephalopathy in people with cirrhosis

Non‐absorbable disaccharides probably leads to lower serious adverse events compared with placebo/no intervention (moderate certainty).

1 finding from 1 review

Non‐absorbable disaccharides vs placebo or no intervention

Non‐serious adverse events (secondary outcome) · prevention and treatment of hepatic encephalopathy in people with cirrhosis

It is very uncertain whether non‐absorbable disaccharides changes non‐serious adverse events (secondary outcome) compared with placebo/no intervention (very low certainty).

1 finding from 1 review