Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

66 questions · 67 findings · 7 reviews

No studies found 16 · 23.9%GRADE not reported 1 · 1.5%Very low 15 · 22.4%Low 15 · 22.4%Moderate 20 · 29.9%High 0 · 0%

LNG‐IUS vs non‐intrauterine progestogen

Regression of EH; by length of · endometrial hyperplasia

LNG‐IUS probably leads to higher regression of EH; by length of compared with non‐intrauterine progestogen (moderate certainty).

2 findings from 1 review

LNG‐IUS vs non‐intrauterine progestogen

Adverse effects associated with hormones:Bleeding/spotting Nausea Weight gain · endometrial hyperplasia

It is very uncertain whether LNG‐IUS changes adverse effects associated with hormones:Bleeding/spotting Nausea… compared with non‐intrauterine progestogen (very low certainty).

1 finding from 1 review

Surgery vs LNG‐IUS

Satisfaction rate: surgery versus LNG‐IUS Endometrial ablation versus LNG‐IUS At 2 years · women with heavy menstrual bleeding

Surgery showed no clear difference in satisfaction rate: surgery versus LNG‐IUS Endometrial ablation… compared with LNG‐IUS (low certainty).

1 finding from 1 review

Surgery vs LNG‐IUS

Proportion of women with adverse events Endometrial ablation versus LNG‐IUS. At one year · women with heavy menstrual bleeding

Surgery probably leads to lower proportion of women with adverse events Endometrial ablation versus… compared with LNG‐IUS (moderate certainty).

1 finding from 1 review

Surgery vs LNG‐IUS

Objective control of bleeding: menstrual loss under 80 ml per cycle LNG‐IUS versus hysterectomy At 1 year · women with heavy menstrual bleeding

Surgery probably leads to higher objective control of bleeding: menstrual loss under 80 ml per cycle… compared with LNG‐IUS (moderate certainty).

1 finding from 1 review

Surgery vs LNG‐IUS

Subjective control of bleeding: PBAC no more than 75 per cycle Endometrial resection or ablation versus LNG‐IUS At 1 year · women with heavy menstrual bleeding

Surgery may leads to higher subjective control of bleeding: PBAC no more than 75 per cycle… compared with LNG‐IUS (low certainty).

1 finding from 1 review

Surgery vs LNG‐IUS

Satisfaction rate: surgery versus LNG‐IUS Endometrial ablation versus LNG‐IUS At 1 year · women with heavy menstrual bleeding

Surgery showed no clear difference in satisfaction rate: surgery versus LNG‐IUS Endometrial ablation… compared with LNG‐IUS (low certainty).

1 finding from 1 review