Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

51 questions · 54 findings · 5 reviews

No studies found 27 · 50%GRADE not reported 0 · 0%Very low 11 · 20.4%Low 13 · 24.1%Moderate 3 · 5.6%High 0 · 0%

Intravenous iron with oral iron vs oral iron

Persistent anaemia symptoms Reported by the women · women with postpartum iron deficiency anaemia

It is very uncertain whether intravenous iron with oral iron changes persistent anaemia symptoms ‐ 1 week Visual Analogue Scale ≥ 7 compared with oral iron (Comparison 6) (very low certainty).

3 findings from 1 review

Intravenous iron vs oral iron

Ferritin (µg/L) · people with preoperative anaemia awaiting major surgery

Intravenous iron therapy may leads to higher ferritin preoperatively postintervention (ng/L) compared with oral iron therapy (low certainty).

1 finding from 1 review

Intravenous iron vs oral iron

Haemoglobin (g/dL) · people with preoperative anaemia awaiting major surgery

Intravenous iron therapy may leads to higher haemoglobin levels at end of preoperative treatment (g/dL) compared with oral iron therapy (low certainty).

2 findings from 1 review

IV or oral iron alone vs no treatment

Red blood cell transfusions (Subnet based on 69 studies including 18,684 participants) · patients at any age with solid cancer or haematological malignancy

IV or oral iron alone showed no clear difference in red blood cell transfusions (Subnet based on 69 studies including… compared with no treatment (low certainty).

1 finding from 1 review

IV or oral iron alone vs no treatment

Overall mortality4 (Subnet based on 71 studies including 21,576 participants) · patients at any age with solid cancer or haematological malignancy

IV or oral iron alone showed no clear difference in overall mortality4 (Subnet based on 71 studies including 21,576… compared with no treatment (low certainty).

1 finding from 1 review