Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

172 questions · 181 findings · 11 reviews

No studies found 35 · 19.3%GRADE not reported 3 · 1.7%Very low 68 · 37.6%Low 70 · 38.7%Moderate 5 · 2.8%High 0 · 0%

Intentional endometrial injury vs no intervention or a sham procedure

Live birth · infertile women or couples attempting to conceive through sexual intercourse or intrauterine insemination (IUI)

Intentional endometrial injury showed no clear difference in live birth (primary analysis) compared with no intervention or a sham procedure (low certainty).

1 finding from 1 review

Intervention not reported

Live birth or ongoing pregnancy: early (EFP) vs late (LFP) follicular phase · infertile women or couples attempting to conceive through sexual intercourse or intrauterine insemination (IUI)

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Clinical pregnancy: early (EFP) vs late (LFP) follicular phase (sensitivity analysis) · infertile women or couples attempting to conceive through sexual intercourse or intrauterine insemination (IUI)

It is very uncertain whether the intervention changes clinical pregnancy: early (EFP) vs late (LFP) follicular phase… (very low certainty).

1 finding from 1 review

Intentional endometrial injury vs no intervention or a sham procedure

Live birth or ongoing pregnancy · infertile women or couples attempting to conceive through sexual intercourse or intrauterine insemination (IUI)

It is very uncertain whether intentional endometrial injury changes live birth or ongoing pregnancy (sensitivity analysis) compared with no intervention or a sham procedure (very low certainty).

1 finding from 1 review

Intentional endometrial injury vs no intervention or a sham procedure

Clinical pregnancy · infertile women or couples attempting to conceive through sexual intercourse or intrauterine insemination (IUI)
2 findings from 1 review

Intervention not reported

Live birth or ongoing pregnancy: prior cycle vs IUI cycle · infertile women or couples attempting to conceive through sexual intercourse or intrauterine insemination (IUI)

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Clinical pregnancy: prior cycle vs IUI cycle (sensitivity analysis) · infertile women or couples attempting to conceive through sexual intercourse or intrauterine insemination (IUI)

It is very uncertain whether the intervention changes clinical pregnancy: prior cycle vs IUI cycle (sensitivity analysis) (very low certainty).

1 finding from 1 review

Progesterone vs no treatment or placebo (route of progesterone administration)

Live birth or ongoing pregnancy · women trying to conceive by intrauterine insemination

Progesterone showed no clear difference in live birth/ongoing pregnancy rate compared with no treatment or placebo (route of progesterone administration) (low certainty).

1 finding from 1 review