Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

426 questions · 433 findings · 18 reviews · Implants and prosthodontics

No studies found 45 · 10.4%GRADE not reported 341 · 78.8%Very low 36 · 8.3%Low 6 · 1.4%Moderate 5 · 1.2%High 0 · 0%

Vertical GBR with non-resorbable titanium-reinforced barriers vs Vertical GBR with resorbable barriers supported by osteosynthesis plates

Perimplant bone loss · Patients with vertically deficient posterior/anterior mandibular ridges needing implants

Vertical GBR with non-resorbable titanium-reinforced barriers showed no clear difference in perimplant bone loss (3 years) compared with vertical GBR with resorbable barriers supported by osteosynthesis…; GRADE not reported.

1 finding from 1 review

Vertical GBR with non-resorbable titanium-reinforced barriers vs Vertical GBR with resorbable barriers supported by osteosynthesis plates

Vertical bone gain · Patients with vertically deficient posterior/anterior mandibular ridges needing implants

Vertical GBR with non-resorbable titanium-reinforced barriers showed no clear difference in vertical bone gain compared with vertical GBR with resorbable barriers supported by osteosynthesis…; GRADE not reported.

1 finding from 1 review

ARP with demineralised bone matrix, single particle size vs ARP with demineralised bone matrix, multiple particle size

Complications (e.g. discomfort, pain and swelling) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…
1 finding from 1 review

ARP with allograft (bone graft) vs ARP with xenograft

Complications (e.g. discomfort, pain and swelling) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…
1 finding from 1 review

ARP with xenograft (bone graft) vs Extraction alone

Complications (e.g. discomfort, pain and swelling) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…
1 finding from 1 review

ARP with alloplast vs ARP with xenograft

Need for additional augmentation prior to implant placement · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…

It is very uncertain whether ARP with alloplast changes need for additional augmentation prior to implant placement compared with ARP with xenograft (very low certainty).

1 finding from 1 review

ARP with alloplast plus barrier membrane vs ARP with alloplast without membrane

Need for additional augmentation prior to implant placement · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…

The review found no eligible studies for this question.

1 finding from 1 review

ARP with alloplast vs Extraction alone

Need for additional augmentation prior to implant placement · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…

The review found no eligible studies for this question.

1 finding from 1 review

ARP with alloplast plus barrier membrane vs ARP with alloplast without membrane

Complications (e.g. discomfort, pain and swelling) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…
1 finding from 1 review

ARP with allograft plus synthetic cell-binding peptide P-15 vs ARP with allograft without P-15

Complications (e.g. discomfort, pain and swelling) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…
1 finding from 1 review

ARP with allograft plus synthetic cell-binding peptide P-15 vs ARP with allograft without P-15

Need for additional augmentation prior to implant placement · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…

The review found no eligible studies for this question.

1 finding from 1 review

ARP with alloplast vs Extraction alone

Complications (e.g. discomfort, pain and swelling) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…
1 finding from 1 review

ARP with xenograft (bone graft) vs Extraction alone

Need for additional augmentation prior to implant placement · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…

It is very uncertain whether ARP with xenograft (bone graft) changes need for additional augmentation prior to implant placement compared with extraction alone (very low certainty).

1 finding from 1 review

ARP with allograft (bone graft) vs ARP with xenograft

Need for additional augmentation prior to implant placement · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…

It is very uncertain whether ARP with allograft changes need for additional augmentation prior to implant placement compared with ARP with xenograft (very low certainty).

1 finding from 1 review

ARP with alloplast vs ARP with xenograft

Complications (e.g. discomfort, pain and swelling) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…
1 finding from 1 review

ARP with demineralised bone matrix, single particle size vs ARP with demineralised bone matrix, multiple particle size

Need for additional augmentation prior to implant placement · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…

The review found no eligible studies for this question.

1 finding from 1 review

One-stage lateral sinus lift with monocortical autogenous bone blocks (iliac crest) vs Two-stage lateral sinus lift with autogenous particulate bone (iliac crest)

Complication (perforation of sinus membrane) at augmented site · Patients with 2 to 7 mm of residual alveolar bone height in the edentulous maxillary sinus floor

One-stage lateral sinus lift with monocortical autogenous bone… showed no clear difference in complications (sinus membrane perforation) compared with two-stage lateral sinus lift with autogenous particulate bone (iliac…; GRADE not reported.

1 finding from 1 review

Amine fluoride/stannous fluoride (AmF/SnF2) mouthwash vs Chlorhexidine mouthwash

Patient satisfaction (desire for future use) · Adults with dental implants and healthy peri-implant soft tissues at baseline

Amine fluoride/stannous fluoride (AmF/SnF2) mouthwash led to higher patient satisfaction (desire for future use) compared with chlorhexidine mouthwash; GRADE not reported.

1 finding from 1 review

Inlay/interposed bone graft (iliac or Bio-Oss block) + longer implants (vertical augmentation) vs Short implants (8 to 11 mm) without augmentation

Severe pain for > 1 week · Patients with atrophic (resorbed) mandibles needing implants

Inlay/interposed bone graft (iliac or Bio-Oss block) + longer… led to higher severe pain for > 1 week compared with short implants (8 to 11 mm) without augmentation; GRADE not reported.

1 finding from 1 review

Brushing vs no treatment

Total anaerobes (colony forming units, log-transformed) · Maxillary complete denture (CD) wearers

Brushing led to lower total anaerobes (colony forming units, log-transformed) compared with no treatment; GRADE not reported.

1 finding from 1 review