Findings

What do systematic reviews say?

777 questions · 792 findings · 40 reviews · Kidney and Transplant

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No studies found 232 · 29.3%GRADE not reported 3 · 0.4%Very low 218 · 27.5%Low 253 · 31.9%Moderate 76 · 9.6%High 10 · 1.3%

Any weight loss intervention vs usual care or control

Body‐mass index (BMI) · people with CKD who are overweight or obese

1 finding from 1 review

Interventions for weight loss in people with chronic kidney disease who are overweight or obese 2021 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 100 participants
Very low

Any weight loss intervention vs usual care or control

Waist circumference · people with CKD who are overweight or obese

1 finding from 1 review

Interventions for weight loss in people with chronic kidney disease who are overweight or obese 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 53 participants
Very low

Any weight loss intervention vs usual care or control

Proteinuria · people with CKD who are overweight or obese

1 finding from 1 review

Interventions for weight loss in people with chronic kidney disease who are overweight or obese 2021 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 84 participants
Very low

Any weight loss intervention vs usual care or control

Systolic blood pressure · people with CKD who are overweight or obese

1 finding from 1 review

Interventions for weight loss in people with chronic kidney disease who are overweight or obese 2021 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 139 participants
Very low

Pharmacological interventions vs placebo

GABA analogue VAS(0 to 10 cm) · uraemic pruritus

1 finding from 1 review

Interventions for itch in people with advanced chronic kidney disease 2020 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 297 participants
High

Pharmacological interventions vs placebo

Montelukast Duo score (0 to 81) and VAS (0 to 10 cm) · uraemic pruritus

1 finding from 1 review

Interventions for itch in people with advanced chronic kidney disease 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 87 participants
Moderate

Pharmacological interventions vs placebo

Sertraline VAS(0 to 10 cm) · uraemic pruritus

1 finding from 1 review

Interventions for itch in people with advanced chronic kidney disease 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 46 participants
Low

Pharmacological interventions vs placebo

Lidocaine Itch relief · uraemic pruritus

1 finding from 1 review

Interventions for itch in people with advanced chronic kidney disease 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 16 participants
Very low

Pharmacological interventions vs placebo

Sodium thalidomide Itch relief · uraemic pruritus

1 finding from 1 review

Interventions for itch in people with advanced chronic kidney disease 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 33 participants
Very low

Pharmacological interventions vs placebo

Doxepin Itch relief · uraemic pruritus

1 finding from 1 review

Interventions for itch in people with advanced chronic kidney disease 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 48 participants
Low

Pharmacological interventions vs placebo

Ondansetron VAS(0 to 10 cm) · uraemic pruritus

1 finding from 1 review

Interventions for itch in people with advanced chronic kidney disease 2020 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 183 participants
High

Pharmacological interventions vs placebo

Kappa‐opioid agonist VAS(0 to 10 cm) · uraemic pruritus

1 finding from 1 review

Interventions for itch in people with advanced chronic kidney disease 2020 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 661 participants
High

Pharmacological interventions vs placebo

Mu‐opioid antagonist VAS(0 to 10 cm) · uraemic pruritus

1 finding from 1 review

Interventions for itch in people with advanced chronic kidney disease 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 62 participants
Low

Pharmacological interventions vs placebo

Nalbuphine VAS(0 to 10 cm) · uraemic pruritus

1 finding from 1 review

Interventions for itch in people with advanced chronic kidney disease 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 179 participants
Low

Pharmacological interventions vs placebo

Cromolyn VAS(0 to 10 cm) · uraemic pruritus

1 finding from 1 review

Interventions for itch in people with advanced chronic kidney disease 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 40 participants
Low

Pharmacological interventions vs placebo

Nicotinamide VAS(0 to 5 cm) · uraemic pruritus

1 finding from 1 review

Interventions for itch in people with advanced chronic kidney disease 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 50 participants
Low

Pharmacological interventions vs placebo

EPO Duo score(0 to 40) · uraemic pruritus

1 finding from 1 review

Interventions for itch in people with advanced chronic kidney disease 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 20 participants
Very low

Pharmacological interventions vs placebo

Cholestyramine 0 to 3 severity scale · uraemic pruritus

1 finding from 1 review

Interventions for itch in people with advanced chronic kidney disease 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 15 participants
Low

Educational interventions and self‐management training vs usual care

Knowledge: kidney disease‐related knowledge · people with CKD

1 finding from 1 review

Interventions for improving health literacy in people with chronic kidney disease 2022 · Cochrane Headline outcomes only
no estimate extracted
15 studies · 2185 participants
Low

Educational interventions and self‐management training vs usual care

Self‐care behaviour · people with CKD

1 finding from 1 review

Interventions for improving health literacy in people with chronic kidney disease 2022 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 913 participants
Low