What do systematic reviews say?

Application of heat vs application of cold

It is very uncertain whether application of heat changes adverse events due to treatment Minor adverse events, reported in… compared with application of cold (very low certainty).

• Interventions for the symptoms and signs resulting from jellyfish stings 2023 · Cochrane Headline outcomes only
  RR 0.5 [0.05, 5.19]
  2 studies · 142 participants
  Very low

Self‐hypnosis or hypnotherapy vs all

• Hypnosis for pain management during labour and childbirth 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 174 participants
  Low

Effervescent tablets vs No treatment (immersion in distilled water)

• Interventions for cleaning dentures in adults 2009 · Cochrane All outcomes
  Moore 1984: soaking methods resulted in significant reduction of total aerobes and anaerobes versus distilled water (paired t test, P < 0.05); three soaking methods (Clorox and Calgon, Polident, Effedent) were less…
  1 study · 12 participants
  GRADE not reported

Brushing vs No treatment (immersion in distilled water)

• Interventions for cleaning dentures in adults 2009 · Cochrane All outcomes
  Moore 1984 found that the seven tested methods were similar and resulted in a significant reduction in total aerobes and anaerobes compared with immersion in distilled water (paired t test, P < 0.05). Some chemical…
  1 study · 12 participants
  GRADE not reported