Findings

What do systematic reviews say?

28 questions · 28 findings · 4 reviews · Haematology

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No studies found 2 · 7.1%GRADE not reported 9 · 32.1%Very low 1 · 3.6%Low 6 · 21.4%Moderate 9 · 32.1%High 1 · 3.6%

Intervention not reported

Adverse events not estimable · Patients with refractory/relapsed Hodgkin lymphoma

1 finding from 1 review

High‐dose chemotherapy followed by autologous stem cell transplantation for patients with relapsed/refractory Hodgkin… 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 100 participants
GRADE not reported

Intervention not reported

Quality of life not reported · Patients with refractory/relapsed Hodgkin lymphoma

1 finding from 1 review

High‐dose chemotherapy followed by autologous stem cell transplantation for patients with relapsed/refractory Hodgkin… 2013 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Intervention not reported

Overall survival · Adult patients with follicular lymphoma

The intervention showed no clear difference in overall survival (moderate certainty).

1 finding from 1 review

High‐dose therapy with autologous stem cell transplantation versus chemotherapy or immuno‐chemotherapy for follicular… 2012 · Cochrane Headline outcomes only
HR 0.97 [0.76, 1.22]
3 studies · 701 participants
Moderate

Intervention not reported

Treatment‐related mortality · Adult patients with follicular lymphoma

The intervention showed no clear difference in treatment‐related mortality (moderate certainty).

1 finding from 1 review

High‐dose therapy with autologous stem cell transplantation versus chemotherapy or immuno‐chemotherapy for follicular… 2012 · Cochrane Headline outcomes only
RR 1.28 [0.25, 6.61]
4 studies · 941 participants
Moderate

Intervention not reported

Progression‐free survival · Adult patients with follicular lymphoma

The intervention probably leads to lower progression‐free survival (moderate certainty).

1 finding from 1 review

High‐dose therapy with autologous stem cell transplantation versus chemotherapy or immuno‐chemotherapy for follicular… 2012 · Cochrane Headline outcomes only
HR 0.42 [0.33, 0.54]
3 studies · 540 participants
Moderate

Intervention not reported

Secondary malignancies AML/MDS · Adult patients with follicular lymphoma

The intervention showed no clear difference in secondary malignancies AML/MDS (low certainty).

1 finding from 1 review

High‐dose therapy with autologous stem cell transplantation versus chemotherapy or immuno‐chemotherapy for follicular… 2012 · Cochrane Headline outcomes only
RR 2.87 [0.7, 11.75]
4 studies · 1023 participants
Low

Intervention not reported

Secondary malignancies Solid cancer · Adult patients with follicular lymphoma

The intervention showed no clear difference in secondary malignancies Solid cancer (low certainty).

1 finding from 1 review

High‐dose therapy with autologous stem cell transplantation versus chemotherapy or immuno‐chemotherapy for follicular… 2012 · Cochrane Headline outcomes only
RR 1.2 [0.25, 5.77]
3 studies · 701 participants
Low

Intervention not reported

Adverse events · Adult patients with follicular lymphoma

1 finding from 1 review

High‐dose therapy with autologous stem cell transplantation versus chemotherapy or immuno‐chemotherapy for follicular… 2012 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 527 participants
Very low