Findings

What do systematic reviews say?

37 questions · 37 findings · 5 reviews · Gynaecology and Fertility

Sort:Best matchNewest Highest certainty Download CSV

No studies found 12 · 32.4%GRADE not reported 0 · 0%Very low 9 · 24.3%Low 14 · 37.8%Moderate 2 · 5.4%High 0 · 0%

Modified natural cycle FET (HCG trigger) vs HT FET

Live birth rate per woman · subfertile women

Modified natural cycle FET (HCG trigger) showed no clear difference in live birth rate per woman compared with HT FET (low certainty).

1 finding from 1 review

Cycle regimens for frozen‐thawed embryo transfer 2017 · Cochrane Headline outcomes only
OR 1.34 [0.88, 2.05]
1 study · 959 participants
Low

Modified natural cycle FET (HCG trigger) vs HT FET

Miscarriage · subfertile women

The review found no eligible studies for this question.

1 finding from 1 review

Cycle regimens for frozen‐thawed embryo transfer 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Modified natural cycle FET (HCG trigger) vs HT FET

Ongoing pregnancy · subfertile women

Modified natural cycle FET (HCG trigger) showed no clear difference in ongoing pregnancy rate per woman compared with HT FET (low certainty).

1 finding from 1 review

Cycle regimens for frozen‐thawed embryo transfer 2017 · Cochrane Headline outcomes only
OR 1.21 [0.8, 1.83]
1 study · 959 participants
Low

Modified natural cycle FET (HCG trigger) vs HT FET

Multiple pregnancy rate · subfertile women

The review found no eligible studies for this question.

1 finding from 1 review

Cycle regimens for frozen‐thawed embryo transfer 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Modified natural cycle FET (HCG trigger) vs HT + GnRHa FET

Live birth rate per woman · subfertile women

Modified natural cycle FET (HCG trigger) showed no clear difference in live birth rate per woman compared with HT + GnRHa suppression FET (low certainty).

1 finding from 1 review

Cycle regimens for frozen‐thawed embryo transfer 2017 · Cochrane Headline outcomes only
OR 1.11 [0.66, 1.87]
1 study · 236 participants
Low

Modified natural cycle FET (HCG trigger) vs HT + GnRHa FET

Miscarriage · subfertile women

Modified natural cycle FET (HCG trigger) showed no clear difference in miscarriage rate per woman compared with HT + GnRHa suppression FET (low certainty).

1 finding from 1 review

Cycle regimens for frozen‐thawed embryo transfer 2017 · Cochrane Headline outcomes only
OR 0.74 [0.25, 2.19]
1 study · 236 participants
Low

Modified natural cycle FET (HCG trigger) vs HT + GnRHa FET

Ongoing pregnancy · subfertile women

The review found no eligible studies for this question.

1 finding from 1 review

Cycle regimens for frozen‐thawed embryo transfer 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Modified natural cycle FET (HCG trigger) vs HT + GnRHa FET

Multiple pregnancy rate · subfertile women

The review found no eligible studies for this question.

1 finding from 1 review

Cycle regimens for frozen‐thawed embryo transfer 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Endometrial resection or ablation vs minimally invasive hysterectomy

Safety Any serious adverse event · heavy menstrual bleeding

Endometrial resection or ablation showed no clear difference in safety Any serious adverse event compared with minimally invasive hysterectomy (moderate certainty).

1 finding from 1 review

Endometrial resection and ablation versus hysterectomy for heavy menstrual bleeding 2021 · Cochrane Headline outcomes only
RR 0.75 [0.35, 1.59]
4 studies · 809 participants
Moderate

Endometrial resection or ablation vs unspecified (or at surgeon's discretion) route of hysterectomy

Safety Any serious adverse event · heavy menstrual bleeding

Endometrial resection/ablation probably leads to lower safety Any serious adverse event compared with unspecified (or at surgeon's discretion) route of hysterectomy (moderate certainty).

1 finding from 1 review

Endometrial resection and ablation versus hysterectomy for heavy menstrual bleeding 2021 · Cochrane Headline outcomes only
RR 0.21 [0.06, 0.8]
2 studies · 374 participants
Moderate

Endometrial resection or ablation vs open hysterectomy

Safety Any serious adverse event · HMB

Endometrial resection or ablation showed no clear difference in safety Any serious adverse events compared with open hysterectomy (low certainty).

1 finding from 1 review

Endometrial resection and ablation versus hysterectomy for heavy menstrual bleeding 2021 · Cochrane Headline outcomes only
RR 1.29 [0.32, 5.2]
2 studies · 247 participants
Low

Metabolomics vs non metabolomics

Live birth rate · Women undergoing IVF/ICSI cycles

Metabolomics showed no clear difference in live birth rate (Delivery of a live fetus after 20 completed weeks… compared with non metabolomics (low certainty).

1 finding from 1 review

Metabolomics for improving pregnancy outcomes in women undergoing assisted reproductive technologies 2018 · Cochrane Headline outcomes only
OR 0.99 [0.69, 1.44]
3 studies · 597 participants
Low

Metabolomics vs non metabolomics

Live birth or ongoing pregnancy · Women undergoing IVF/ICSI cycles

Metabolomics showed no clear difference in live birth rate or ongoing pregnancy (Delivery of a live fetus after… compared with non metabolomics (low certainty).

1 finding from 1 review

Metabolomics for improving pregnancy outcomes in women undergoing assisted reproductive technologies 2018 · Cochrane Headline outcomes only
OR 1.02 [0.77, 1.35]
4 studies · 924 participants
Low

Metabolomics vs non metabolomics

Clinical pregnancy (Presence of a fetal heart on ultrasound scan at seven weeks of gestation) · Women undergoing IVF/ICSI cycles

Metabolomics showed no clear difference in clinical pregnancy (Presence of a fetal heart on ultrasound scan at… compared with non metabolomics (low certainty).

1 finding from 1 review

Metabolomics for improving pregnancy outcomes in women undergoing assisted reproductive technologies 2018 · Cochrane Headline outcomes only
OR 1.11 [0.85, 1.45]
4 studies · 924 participants
Low

Metabolomics vs non metabolomics

Ectopic pregnancy · Women undergoing IVF/ICSI cycles

It is very uncertain whether metabolomics changes ectopic pregnancy (a pregnancy in which the fetus develops outside… compared with non metabolomics (very low certainty).

1 finding from 1 review

Metabolomics for improving pregnancy outcomes in women undergoing assisted reproductive technologies 2018 · Cochrane Headline outcomes only
OR 3 [0.12, 74.07]
1 study · 417 participants
Very low

hCG vs no ovulation trigger

Live birth rate Live fetus delivered beyond 20 completed weeks' gestation · women with anovulatory infertility undergoing ovulation induction with clomiphene citrate

Human chorionic gonadotrophin showed no clear difference in live birth rate Live fetus delivered beyond 20 completed weeks'… compared with no ovulation trigger (low certainty).

1 finding from 1 review

Ovulation triggers in anovulatory women undergoing ovulation induction 2014 · Cochrane Headline outcomes only
OR 0.97 [0.52, 1.83]
305 participants
Low

Laparoscopic vs diagnostic laparoscopy

fetal loss per couple randomised · patients with subfertility associated with endometriosis

Laparoscopic surgery showed no clear difference in fetal loss per couple randomised compared with diagnostic laparoscopy (low certainty).

1 finding from 1 review

Laparoscopic surgery for subfertility associated with endometriosis 2010 · Cochrane Headline outcomes only
OR 1.33 [0.6, 2.94]
2 studies · 437 participants
Low