Global state: Needing restraints or seclusion ‐ by 12 hours · people with psychosis‐induced aggression
HALOPERIDOL + PROMETHAZINE showed no clear difference in global state: Needing restraints or seclusion ‐ by 12 hours compared with ANTIPSYCHOTIC ‐ ZIPRASIDONE (moderate certainty).
1 finding from 1 review
Adverse effects: Specific and serious adverse effect ‐ by 24 hours Central nervous system ‐ excessive sedation · people with psychosis‐induced aggression
HALOPERIDOL + PROMETHAZINE showed no clear difference in adverse effects: Specific and serious adverse effect ‐ by 24 hours… compared with ANTIPSYCHOTIC ‐ ZIPRASIDONE (low certainty).
1 finding from 1 review
Adverse effect: Specific ‐ Death · people with psychosis‐induced aggression
1 finding from 1 review
Service outcomes: Not discharged ‐ by 2 weeks · people with psychosis‐induced aggression
1 finding from 1 review
Aggression · people with psychosis‐induced aggression
1 finding from 1 review
Economic outcomes: Cost of care · people with psychosis‐induced aggression
1 finding from 1 review
Tranquil or asleep: Not tranquil or asleep ‐ by 30 mins · people with psychosis‐induced aggression
HALOPERIDOL + PROMETHAZINE leads to lower tranquil or asleep: Not tranquil or asleep ‐ by 30 mins compared with BENZODIAZEPINES ‐ LORAZEPAM (high certainty).
1 finding from 1 review
Global state: Needing restraints or seclusion ‐ by 12 hours · people with psychosis‐induced aggression
HALOPERIDOL + PROMETHAZINE showed no clear difference in global state: Needing restraints or seclusion ‐ by 12 hours compared with BENZODIAZEPINES ‐ LORAZEPAM (moderate certainty).
1 finding from 1 review
Adverse effects: Specific and serious adverse effect ‐ by 24 hours Central nervous system ‐ excessive sedation · people with psychosis‐induced aggression
1 finding from 1 review
Adverse effect: Specific ‐ Death · people with psychosis‐induced aggression
1 finding from 1 review
Service outcomes: Not discharged ‐ by 4 hours · people with psychosis‐induced aggression
HALOPERIDOL + PROMETHAZINE showed no clear difference in service outcomes: Not discharged ‐ by 4 hours compared with BENZODIAZEPINES ‐ LORAZEPAM (high certainty).
1 finding from 1 review
Aggression · people with psychosis‐induced aggression
1 finding from 1 review
Economic outcomes: Cost of care · people with psychosis‐induced aggression
1 finding from 1 review
Tranquil or asleep: Not tranquil or asleep · people with psychosis‐induced aggression
HALOPERIDOL + PROMETHAZINE leads to higher tranquil or asleep: Not tranquil or asleep compared with BENZODIAZEPINES ‐ MIDAZOLAM (high certainty).
1 finding from 1 review
Global outcome ‐ need for restraint or seclusion · people with psychosis‐induced aggression
HALOPERIDOL + PROMETHAZINE showed no clear difference in global state: Needing restraints or seclusion‐ by 2 hours compared with BENZODIAZEPINES ‐ MIDAZOLAM (moderate certainty).
1 finding from 1 review
Adverse effect: Specific ‐ Death · people with psychosis‐induced aggression
1 finding from 1 review
Not discharged from hospital · people with psychosis‐induced aggression
HALOPERIDOL + PROMETHAZINE showed no clear difference in service outcomes: Not discharged ‐ compared with BENZODIAZEPINES ‐ MIDAZOLAM (high certainty).
1 finding from 1 review
Specific behavioursAggression · people with psychosis‐induced aggression
1 finding from 1 review
no estimate extracted
4 participants
GRADE not reported
Economic outcomes: Cost of care · people with psychosis‐induced aggression
1 finding from 1 review
Tranquil or asleep: Not tranquil or asleep ‐ by 30 mins · people with psychosis‐induced aggression
HALOPERIDOL + PROMETHAZINE showed no clear difference in tranquil or asleep: Not tranquil or asleep ‐ by 30 mins compared with ANTIPSYCHOTIC ‐ OLANZAPINE (high certainty).
1 finding from 1 review