Menstrual blood loss: improvement rates · women with heavy menstrual bleeding
Antifibrinolytics may leads to higher menstrual blood loss: improvement rates (overall) compared with progestogens (low certainty).
1 finding from 1 review
Adverse events (any) · women with heavy menstrual bleeding
Antifibrinolytics may leads to lower adverse events (any) compared with progestogens (low certainty).
1 finding from 1 review
Thromboembolic events · women with heavy menstrual bleeding
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Menstrual blood loss: mean loss · women with heavy menstrual bleeding
1 finding from 1 review
Mortality. · adult parapneumonic effusions and empyema
Fibrinolytics showed no clear difference in mortality. compared with placebo (moderate certainty).
1 finding from 1 review
Referral for thoracic surgery (open or thorascopic) · adult parapneumonic effusions and empyema
Fibrinolytics may leads to lower referral for thoracic surgery. compared with placebo (low certainty).
1 finding from 1 review
Overall treatment failure, including mortality, thoracic surgery or referral for further fibrinolytic therapy · adult parapneumonic effusions and empyema
It is very uncertain whether fibrinolytics changes overall treatment failure, including mortality, thoracic surgery or… compared with placebo (very low certainty).
1 finding from 1 review
Serious adverse events · adult parapneumonic effusions and empyema
Fibrinolytics showed no clear difference in serious adverse events compared with placebo (low certainty).
1 finding from 1 review
Number of participants with any bleeding · People with a haematological disorder
1 finding from 1 review
Thromboembolism · People with a haematological disorder
1 finding from 1 review
Mortality (all‐cause) ‐ not reported · People with a haematological disorder
1 finding from 1 review
Number of platelet transfusions per participant up to 30 days from study entry · People with a haematological disorder
1 finding from 1 review
Adverse events associated with transfusion · People with a haematological disorder
1 finding from 1 review
Adverse events of antifibrinolytic agents · People with a haematological disorder
1 finding from 1 review
Quality of life ‐ not reported · People with a haematological disorder
1 finding from 1 review
Intervention not reported
Mean total blood loss (mL: antifibrinolytics vs placebo · children undergoing surgery for scoliosis
1 finding from 1 review
Intervention not reported
Number of participants receiving transfusion with allogeneic blood: antifibrinolytics vs placebo · children undergoing surgery for scoliosis
It is very uncertain whether the intervention changes number of participants receiving transfusion with allogeneic blood:… (very low certainty).
1 finding from 1 review
Intervention not reported
Mean total blood transfused (mL): antifibrinolytics vs placebo · children undergoing surgery for scoliosis
1 finding from 1 review
Intervention not reported
Number of participants receiving blood transfusion: antifibrinolytics vs placebo · children undergoing surgery for scoliosis
It is very uncertain whether the intervention changes number of participants receiving blood transfusion:… (very low certainty).
1 finding from 1 review
Intervention not reported
Total studies: 47 Total participants: 4398 · individuals undergoing planned hip or knee replacement surgery Interventions: antifibrinolytics (tranexamic acid, aprotinin or…
1 finding from 1 review
no estimate extracted
47 participants
GRADE not reported