Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

29 questions · 30 findings · 2 reviews · Eyes and Vision

No studies found 5 · 16.7%GRADE not reported 0 · 0%Very low 0 · 0%Low 14 · 46.7%Moderate 9 · 30%High 2 · 6.7%

Oral long‐chain omega‐3 PUFAs vs oral omega‐6 PUFAs

Change in tear osmolarity (measured in mOsmol/L, with reductions in osmolarity indicating clinical improvement) at 1‐month (with actual · people with dry eyea

Oral long‐chain omega‐3 PUFAs showed no clear difference in change in tear osmolarity (measured in mOsmol/L, with reductions in… compared with oral omega‐6 PUFAs (low certainty).

1 finding from 1 review

Oral long‐chain omega‐3 PUFAs vs placebo or no treatment

Change in tear osmolarity (measured in mOsmol/L, with reductions in osmolarity indicating clinical improvement) at 1‐month (with actual · people with dry eyea

Oral long‐chain omega‐3 PUFAs (ie, EPA and DHA) showed no clear difference in change in tear osmolarity (measured in mOsmol/L, with reductions in… compared with placebo or no treatment (low certainty).

1 finding from 1 review