Findings

What do systematic reviews say?

25 questions · 25 findings · 3 reviews · Hepato-Biliary

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No studies found 5 · 20%GRADE not reported 0 · 0%Very low 19 · 76%Low 1 · 4%Moderate 0 · 0%High 0 · 0%

Glucocorticosteroids vs no intervention

Early mortality (mortality up to 90 days) · participants with alcoholic hepatitis (all severity)

It is very uncertain whether glucocorticosteroids changes early mortality (mortality up to 90 days) compared with no intervention (very low certainty).

1 finding from 1 review

Pharmacological interventions for alcoholic liver disease (alcohol‐related liver disease) 2017 · Cochrane Headline outcomes only
OR 1 [0.71, 1.39]
4 studies · 672 participants
Very low

Propylthiouracil vs no intervention

Early mortality (mortality up to 90 days) · participants with alcoholic hepatitis (all severity)

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for alcoholic liver disease (alcohol‐related liver disease) 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Glucocorticosteroids vs no intervention

Early mortality (mortality up to 90 days) · participants with severe alcoholic hepatitis

It is very uncertain whether glucocorticosteroids changes early mortality (mortality up to 90 days) compared with no intervention (very low certainty).

1 finding from 1 review

Pharmacological interventions for alcoholic liver disease (alcohol‐related liver disease) 2017 · Cochrane Headline outcomes only
OR 1.01 [0.71, 1.43]
2 studies · 607 participants
Very low

Pentoxifylline vs no intervention

Early mortality (mortality up to 90 days) · participants with severe alcoholic hepatitis

It is very uncertain whether pentoxifylline changes early mortality (mortality up to 90 days) compared with no intervention (very low certainty).

1 finding from 1 review

Pharmacological interventions for alcoholic liver disease (alcohol‐related liver disease) 2017 · Cochrane Headline outcomes only
OR 1.18 [0.81, 1.74]
1 study · 545 participants
Very low

Pentoxifylline vs no intervention

Early mortality (mortality up to 90 days) · participants with alcoholic hepatitis (all severity)

It is very uncertain whether pentoxifylline changes early mortality (mortality up to 90 days) compared with no intervention (very low certainty).

1 finding from 1 review

Pharmacological interventions for alcoholic liver disease (alcohol‐related liver disease) 2017 · Cochrane Headline outcomes only
OR 1.18 [0.81, 1.74]
1 study · 545 participants
Very low