Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

38 questions · 41 findings · 6 reviews · Gut

No studies found 6 · 14.6%GRADE not reported 0 · 0%Very low 24 · 58.5%Low 10 · 24.4%Moderate 1 · 2.4%High 0 · 0%

Infliximab 5–10 mg/kg vs placebo

Clinical remission defined as absence of any draining fistulas at ≥ 2 consecutive visits, at a median 12 weeks · Patients with active Crohn's disease

It is very uncertain whether infliximab 5–10 mg/kg changes clinical remission defined as absence of any draining fistulas at ≥… compared with placebo (very low certainty).

1 finding from 1 review

Infliximab 5–10 mg/kg vs placebo

Clinical response defined as reduction of 50% in the number of draining fistula at ≥ 2 consecutive visits, at a median length of time of 12 weeks · Patients with active Crohn's disease

It is very uncertain whether infliximab 5–10 mg/kg changes clinical response defined as reduction of 50% in the number of… compared with placebo (very low certainty).

1 finding from 1 review

Intervention not reported

Minimally invasive step‐up approach: planned surgery vs. continued percutaneous drainage · people with necrotising pancreatitis

It is very uncertain whether the intervention changes minimally invasive step‐up approach: planned surgery vs. continued… (very low certainty).

1 finding from 1 review

Intervention not reported

Open surgical drainage versus EUS‐guided drainage · patients with pancreatic pseudocysts

It is very uncertain whether the intervention changes open surgical drainage versus EUS‐guided drainage (very low certainty).

1 finding from 1 review

Intervention not reported

Endoscopic drainage versus EUS‐guided drainage · patients with pancreatic pseudocysts

It is very uncertain whether the intervention changes endoscopic drainage versus EUS‐guided drainage (very low certainty).

1 finding from 1 review

Intervention not reported

EUS‐guided drainage with nasocystic drainage versus EUS‐guided drainage · patients with pancreatic pseudocysts
1 finding from 1 review

Intervention not reported

Open surgical drainage versus EUS‐guided drainage · patients with pancreatic pseudocysts
1 finding from 1 review

Intervention not reported

Open surgical drainage versus EUS‐guided drainage Scale from: 0 to 100. Higher indicates better · patients with pancreatic pseudocysts
1 finding from 1 review

Intervention not reported

Endoscopic drainage versus EUS‐guided drainage · patients with pancreatic pseudocysts

It is very uncertain whether the intervention changes endoscopic drainage versus EUS‐guided drainage (very low certainty).

1 finding from 1 review

Intervention not reported

EUS‐guided drainage with nasocystic drainage versus EUS‐guided drainage · patients with pancreatic pseudocysts

The intervention may leads to lower EUS‐guided drainage with nasocystic drainage versus EUS‐guided… (low certainty).

1 finding from 1 review

Early vs late drain removal following pancreatic surgery

All‐cause mortality · people undergoing elective pancreatic resections

It is very uncertain whether early changes mortality compared with late drain removal following pancreatic surgery (very low certainty).

2 findings from 1 review