Sepsis‐specific neonatal mortality · neonates with possible serious bacterial infection
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Treatment failure · neonates with possible serious bacterial infection
Comparison 2: 2 days oral amoxicillin + injectable gentamicin… showed no clear difference in treatment failure compared with 7 days injectable benzylpenicillin + injectable gentamicin (moderate certainty).
1 finding from 1 review
Adverse events · neonates with possible serious bacterial infection
1 finding from 1 review
Neonatal mortality · neonates with possible serious bacterial infection
Comparison 2: 2 days injectable benzylpenicillin + injectable… showed no clear difference in neonatal mortality compared with 7 days injectable benzylpenicillin + injectable gentamicin (low certainty).
1 finding from 1 review
Early neonatal mortality · neonates with possible serious bacterial infection
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Late neonatal mortality · neonates with possible serious bacterial infection
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Sepsis‐specific neonatal mortality · neonates with possible serious bacterial infection
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Treatment failure · neonates with possible serious bacterial infection
Comparison 2: 2 days injectable benzylpenicillin + injectable… showed no clear difference in treatment failure compared with 7 days injectable benzylpenicillin + injectable gentamicin (moderate certainty).
1 finding from 1 review
Adverse events · neonates with possible serious bacterial infection
Comparison 2: 2 days injectable benzylpenicillin + injectable… showed no clear difference in adverse events compared with 7 days injectable benzylpenicillin + injectable gentamicin (moderate certainty).
1 finding from 1 review
Intervention not reported
Presence of PDA on third to fourth day of life (after 72 hours of treatment) · preterm or low birth weight infants with risk of having PDA on day 3 to 4 of life
The intervention probably leads to lower presence of PDA on third to fourth day of life (after 72 hours of… (moderate certainty).
1 finding from 1 review
Intervention not reported
Presence of PDA on third day of life (72 hours of treatment) · preterm or low birth weight infants with risk of having PDA on day 3 to 4 of life
1 finding from 1 review
Intervention not reported
Presence of PDA on day 3 or 4 of life (after 72 hours of treatment) · preterm or low birth weight infants with risk of having PDA on day 3 to 4 of life
The intervention may leads to lower presence of PDA on day 3 or 4 of life (after 72 hours of treatment) (low certainty).
1 finding from 1 review
Mortality Mortality at latest · preterm or low birth weight infants
1 finding from 1 review
Neurodevelopmental disability · preterm or low birth weight infants
1 finding from 1 review
Hyponatraemia (< 130 mmol/L) · preterm or low birth weight infants
1 finding from 1 review
Hypernatraemia (≥ 150 mmol/L) · preterm or low birth weight infants
It is very uncertain whether early and late (day 1 to 28 after birth) higher changes hypernatraemia (≥ 150 mmol/L) compared with lower sodium intake (very low certainty).
1 finding from 1 review
Postnatal growth failure (weight < 10th percentile) · preterm or low birth weight infants
1 finding from 1 review
Necrotising enterocolitis · preterm or low birth weight infants
1 finding from 1 review
Chronic lung disease · preterm or low birth weight infants
1 finding from 1 review
Hyponatraemia (< 130 mmol/L) · preterm or low birth weight infants
Late (seven days or more following birth) higher may leads to lower hyponatraemia (< 130 mmol/L) compared with lower sodium intake (low certainty).
1 finding from 1 review