Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

96 questions · 96 findings · 7 reviews · Headline outcomes only

No studies found 35 · 36.5%GRADE not reported 6 · 6.3%Very low 13 · 13.5%Low 20 · 20.8%Moderate 22 · 22.9%High 0 · 0%

Low‐dose colchicine vs placebo

Participant global assessment of treatment success: proportion with 50% or greater decrease in pain score from baseline ‐ 32 to 36 hours · acute gout

Low‐dose colchicine may leads to higher participant global assessment of treatment success: proportion with… compared with placebo (low certainty).

1 finding from 1 review

Low‐dose colchicine vs NSAIDs

Global assessment of treatment success · acute gout

Low‐dose colchicine showed no clear difference in participant global assessment of treatment success: Completely… compared with NSAIDs (low certainty).

1 finding from 1 review

Low‐dose colchicine vs NSAIDs

Reduction of inflammation ‐ not measured · acute gout

The review found no eligible studies for this question.

1 finding from 1 review

Low‐dose colchicine vs NSAIDs

Function of target joint ‐ not measured · acute gout

The review found no eligible studies for this question.

1 finding from 1 review

Low‐dose colchicine vs NSAIDs

Number of participants reporting an adverse event · acute gout

Low‐dose colchicine showed no clear difference in total number of participants reporting adverse events compared with NSAIDs (low certainty).

1 finding from 1 review

Low‐dose colchicine vs placebo

Reduction of inflammation ‐ not measured · acute gout

The review found no eligible studies for this question.

1 finding from 1 review

Low‐dose colchicine vs placebo

Function of target joint ‐ not measured · acute gout

The review found no eligible studies for this question.

1 finding from 1 review