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Evidence found and GRADE certainty

34 questions · 34 findings · 5 reviews · Movement Disorders

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No studies found 3 · 8.8%GRADE not reported 0 · 0%Very low 7 · 20.6%Low 10 · 29.4%Moderate 8 · 23.5%High 6 · 17.6%

Botulinum toxin type A vs placebo

Adverse events (reported at any time) (2 RCT, 169 participants) · adults with blepharospasm

Botulinum toxin type A showed no clear difference in adverse events (reported at any time) (2 RCT, 169 participants) compared with placebo (low certainty).

1 finding from 1 review

Botulinum toxin type A vs placebo

Tolerability (number of dropouts; reported at any time) (2 RCT, 169 participants) · adults with blepharospasm

Botulinum toxin type A showed no clear difference in tolerability (number of dropouts; reported at any time) (2 RCT, 169… compared with placebo (moderate certainty).

1 finding from 1 review

Botulinum neurotoxin B vs placebo

Withdrawals due to adverse events · adults with cervical dystonia

Botulinum neurotoxin B showed no clear difference in proportion of withdrawals due to adverse events compared with placebo (low certainty).

1 finding from 1 review

Botulinum neurotoxin B vs placebo

Proportion of participants with adverse events · adults with cervical dystonia

It is very uncertain whether botulinum neurotoxin B changes proportion of participants with adverse events compared with placebo (very low certainty).

1 finding from 1 review