Findings

What do systematic reviews say?

21 questions · 32 findings · 1 reviews · Gynaecological, Neuro-oncology and Orphan Cancer

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No studies found 0 · 0%GRADE not reported 14 · 43.8%Very low 18 · 56.3%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Risk‐reducing salpingo‐oophorectomy (RRSO) vs no RRSO according to BRCA mutation status

Overall survival: BRCA2 only

It is very uncertain whether risk‐reducing salpingo‐oophorectomy (RRSO) changes overall survival: BRCA2 only compared with no RRSO according to BRCA mutation status (very low certainty).

1 finding from 1 review

Risk‐reducing bilateral salpingo‐oophorectomy in women with BRCA1 or BRCA2 mutations 2018 · Cochrane Headline outcomes only
HR 0.44 [0.23, 0.85]
2 studies · 2122 participants
Very low