Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

65 questions · 65 findings · 8 reviews · Headline outcomes only

No studies found 16 · 24.6%GRADE not reported 9 · 13.8%Very low 16 · 24.6%Low 7 · 10.8%Moderate 16 · 24.6%High 1 · 1.5%

Betamethasone vs usual care

Respiratory distress syndrome · women undergoing planned elective caesarean section at 37 weeks' gestation and beyond for singleton pregnancy

Effect of antenatal corticosteroids (betamethasone) showed no clear difference in respiratory distress syndrome (RDS) compared with usual care prior to planned caesarean at term on maternal and… (low certainty).

1 finding from 1 review

Betamethasone vs usual care

Transient tachypnoea of the neonate (TTN) · women undergoing planned elective caesarean section at 37 weeks' gestation and beyond for singleton pregnancy

Effect of antenatal corticosteroids (betamethasone) showed no clear difference in transient tachypnoea of the neonate (TTN) compared with usual care prior to planned caesarean at term on maternal and… (low certainty).

1 finding from 1 review

Betamethasone vs usual care

Admission to neonatal special care (all levels) for respiratory morbidity · women undergoing planned elective caesarean section at 37 weeks' gestation and beyond for singleton pregnancy

Effect of antenatal corticosteroids (betamethasone) probably leads to lower admission to neonatal special care (all levels) for respiratory… compared with usual care prior to planned caesarean at term on maternal and… (moderate certainty).

1 finding from 1 review

Betamethasone vs usual care

Need for mechanical ventilation · women undergoing planned elective caesarean section at 37 weeks' gestation and beyond for singleton pregnancy

It is very uncertain whether effect of antenatal corticosteroids (betamethasone) changes need for mechanical ventilation compared with usual care prior to planned caesarean at term on maternal and… (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Oral classical immunosuppressants (betamethasone) vs oral classical immunosuppressants (azathioprine, methotrexate, prednisolone)

Short‐term hair regrowth ≥ 75% (between 12 and 26 weeks of · adults with alopecia areata

Summary of findings table ‐ Oral classical immunosuppressants… showed no clear difference in short‐term hair regrowth ≥ 75% (between 12 and 26 weeks of compared with oral classical immunosuppressants (azathioprine, methotrexate,… (low certainty).

1 finding from 1 review

Summary of findings table ‐ Intralesional classical immunosuppresants (betamethasone or triamcinolone) vs placebo

Short‐term hair regrowth ≥ 75% (between 12 and 26 weeks of · adults with alopecia areata

It is very uncertain whether summary of findings table ‐ Intralesional classical… changes short‐term hair regrowth ≥ 75% (between 12 and 26 weeks of compared with placebo (very low certainty).

1 finding from 1 review