Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

26 questions · 27 findings · 3 reviews · Kidney and Transplant

No studies found 3 · 11.1%GRADE not reported 0 · 0%Very low 3 · 11.1%Low 9 · 33.3%Moderate 8 · 29.6%High 4 · 14.8%

Mycophenolate mofetil vs azathioprine (AZA)

Acute rejection, steroid resistant/antibody treated As reported in the articles · patients with kidney transplant recipients

Mycophenolate mofetil (MMF) leads to lower acute rejection, steroid resistant/antibody treated As reported in… compared with azathioprine (AZA) (high certainty).

1 finding from 1 review

Mycophenolate mofetil vs azathioprine (AZA)

Infection, CMV tissue invasive As reported in the articles · patients with kidney transplant recipients

Mycophenolate mofetil (MMF) leads to higher infection, CMV tissue invasive As reported in the articles compared with azathioprine (AZA) (high certainty).

1 finding from 1 review

Mycophenolate mofetil vs azathioprine (AZA)

Acute rejection, total Any treated acute rejection, including biopsy‐proven · patients with kidney transplant recipients

Mycophenolate mofetil (MMF) leads to lower acute rejection, total Any treated acute rejection, including… compared with azathioprine (AZA) (high certainty).

1 finding from 1 review

Mycophenolate mofetil vs azathioprine (AZA)

Chronic allograft nephropathy Biopsy required in 2 RCTs, one study with optional biopsy · patients with kidney transplant recipients

Mycophenolate mofetil (MMF) may leads to lower chronic allograft nephropathy Biopsy required in 2 RCTs, one study… compared with azathioprine (AZA) (low certainty).

1 finding from 1 review