What do systematic reviews say?

Topical antimicrobial agent vs alternative antimicrobial agent

• Topical treatment for facial burns 2020 · Cochrane Headline outcomes only
  no estimate extracted
  142 participants
  Low

Topical antimicrobial agent vs alternative antimicrobial agent

It is very uncertain whether topical antimicrobial changes infection (until wound healing) compared with alternative antimicrobial agent (very low certainty).

• Topical treatment for facial burns 2020 · Cochrane Headline outcomes only
  RR 0.73 [0.46, 1.17]
  15 participants
  Very low

Topical antimicrobial agent vs alternative antimicrobial agent

The review found no eligible studies for this question.

• Topical treatment for facial burns 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Topical antimicrobial agent vs alternative antimicrobial agent

The review found no eligible studies for this question.

• Topical treatment for facial burns 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Topical antimicrobial agent vs alternative antimicrobial agent

The review found no eligible studies for this question.

• Topical treatment for facial burns 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Antimicrobial vs placebo/no treatment

• Antimicrobial drugs for treating cholera 2014 · Cochrane Headline outcomes only
  no estimate extracted
  19 studies · 1013 participants
  Moderate

Antimicrobial vs placebo/no treatment

• Antimicrobial drugs for treating cholera 2014 · Cochrane Headline outcomes only
  no estimate extracted
  18 studies · 1042 participants
  Moderate

Antimicrobial vs placebo/no treatment

• Antimicrobial drugs for treating cholera 2014 · Cochrane Headline outcomes only
  no estimate extracted
  11 studies · 1201 participants
  Moderate

Antimicrobial vs placebo/no treatment

• Antimicrobial drugs for treating cholera 2014 · Cochrane Headline outcomes only
  no estimate extracted
  12 studies · 740 participants
  Moderate

Antimicrobial vs placebo/no treatment

• Antimicrobial drugs for treating cholera 2014 · Cochrane Headline outcomes only
  no estimate extracted
  7 studies · 299 participants
  GRADE not reported

Topical antimicrobial agents (non‐dressing) vs topical non‐antimicrobial agent

It is very uncertain whether topical antimicrobial agents (non‐dressing) changes proportion of wounds healed Up to 24 weeks' compared with non‐antimicrobial topical agents (non‐dressing) (very low certainty).

• Topical antimicrobial agents for treating foot ulcers in people with diabetes 2017 · Cochrane Headline outcomes only
  RR 2.82 [0.56, 14.23]
  3 studies · 112 participants
  Very low

Topical antimicrobial agents (non‐dressing) vs topical non‐antimicrobial agent

The review found no eligible studies for this question.

• Topical antimicrobial agents for treating foot ulcers in people with diabetes 2017 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Topical antimicrobial agents (non‐dressing) vs topical non‐antimicrobial agent

Topical antimicrobial agents (non‐dressing) showed no clear difference in resolution of infection Up to 24 weeks' compared with non‐antimicrobial topical agents (non‐dressing) (low certainty).

• Topical antimicrobial agents for treating foot ulcers in people with diabetes 2017 · Cochrane Headline outcomes only
  RR 1.16 [0.54, 2.51]
  1 study · 40 participants
  Low

Topical antimicrobial agents (non‐dressing) vs topical non‐antimicrobial agent

• Topical antimicrobial agents for treating foot ulcers in people with diabetes 2017 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 81 participants
  Very low

Topical antimicrobial agent vs topical non‐antimicrobial agent

The review found no eligible studies for this question.

• Topical treatment for facial burns 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Topical antimicrobial agent vs topical non‐antimicrobial agent

Topical antimicrobial agent showed no clear difference in time to complete wound healing (time to event data) (6 months) compared with topical non‐antimicrobial agent (moderate certainty).

• Topical treatment for facial burns 2020 · Cochrane Headline outcomes only
  no estimate extracted
  39 participants
  Moderate
• Topical treatment for facial burns 2020 · Cochrane Headline outcomes only
  no estimate extracted
  60 participants
  Low

Topical antimicrobial agent vs topical non‐antimicrobial agent

Topical antimicrobial agent showed no clear difference in proportion of wounds completely healed within 10 days (10 days) compared with topical non‐antimicrobial agent (low certainty).

• Topical treatment for facial burns 2020 · Cochrane Headline outcomes only
  RR 0.94 [0.68, 1.29]
  39 participants
  Low

Topical antimicrobial agent vs topical non‐antimicrobial agent

The review found no eligible studies for this question.

• Topical treatment for facial burns 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Topical antimicrobial agent vs topical non‐antimicrobial agent

It is very uncertain whether topical antimicrobial agent changes infection (unclear compared with topical non‐antimicrobial agent (very low certainty).

• Topical treatment for facial burns 2020 · Cochrane Headline outcomes only
  RR 0.38 [0.12, 1.21]
  40 participants
  Very low

Topical antimicrobial agent vs growth factor

It is very uncertain whether topical antimicrobial agent changes proportion of wounds healed compared with growth factor (very low certainty).

• Topical antimicrobial agents for treating foot ulcers in people with diabetes 2017 · Cochrane Headline outcomes only
  RR 0.5 [0.28, 0.89]
  1 study · 40 participants
  Very low