Respiratory failure · symptomatic neonates born through meconium‐stained amniotic fluid
Antibiotics showed no clear difference in incidence of respiratory failure compared with control (no antibiotics) (low certainty).
1 finding from 1 review
Incidence of confirmed sepsis in first 28 days · asymptomatic neonates born through meconium‐stained amniotic fluid
1 finding from 1 review
Mortality before hospital discharge · asymptomatic neonates born through meconium‐stained amniotic fluid
Antibiotics showed no clear difference in mortality (before discharge) compared with control (no antibiotics) (low certainty).
1 finding from 1 review
Duration of oxygen therapy (hours) · asymptomatic neonates born through meconium‐stained amniotic fluid
1 finding from 1 review
Clinical failure rate (failure defined as a lack of cure or improvement) · patients with uncomplicated acute maxillary sinusitis
1 finding from 1 review
Patient satisfaction: delayed (prescription collection) versus no antibiotics · respiratory infections
Summary of findings table ‐ Delayed antibiotics probably leads to higher patient satisfaction: delayed (prescription collection) versus no… compared with no antibiotics (moderate certainty).
1 finding from 1 review
Reconsultations · respiratory infections
Summary of findings table ‐ Delayed antibiotics showed no clear difference in reconsultation rate: delayed (all strategies) versus no antibiotics compared with no antibiotics (moderate certainty).
1 finding from 1 review
Adverse effects of antibiotics (diarrhoea, vomiting, rash): delayed versus no antibiotics · respiratory infections
1 finding from 1 review
Antibiotic use: delayed (all strategies) versus immediate antibiotics · respiratory infections
Summary of findings table ‐ Delayed antibiotics probably leads to lower antibiotic use: delayed (all strategies) versus immediate antibiotics compared with immediate antibiotics (moderate certainty).
1 finding from 1 review
Patient satisfaction: delayed (all strategies) versus immediate antibiotics · respiratory infections
Summary of findings table ‐ Delayed antibiotics showed no clear difference in patient satisfaction: delayed (all strategies) versus immediate… compared with immediate antibiotics (moderate certainty).
1 finding from 1 review
Reconsultations · respiratory infections
Summary of findings table ‐ Delayed antibiotics showed no clear difference in reconsultation rate: delayed (all strategies) versus immediate… compared with immediate antibiotics (moderate certainty).
1 finding from 1 review
Adverse effects of antibiotics · respiratory infections
1 finding from 1 review
Antibiotic use: delayed (all strategies) versus no antibiotics · respiratory infections
Summary of findings table ‐ Delayed antibiotics probably leads to higher antibiotic use: delayed (all strategies) versus no antibiotics compared with no antibiotics (moderate certainty).
1 finding from 1 review
Need for additional IV or oral antibiotics · adults and children with cystic fibrosis (during acute exacerbations of lung disease)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Exacerbations · Adults (aged 40 or over) with COPD presenting with 1 or more exacerbations in the previous year. The 2 larger studies (Albert 2011; Sethi…
Antibiotics probably leads to lower number of people with one or more exacerbations WMD of compared with placebo (moderate certainty).
1 finding from 1 review
Annual Exacerbation Rates · Adults (aged 40 or over) with COPD presenting with 1 or more exacerbations in the previous year. The 2 larger studies (Albert 2011; Sethi…
Antibiotics probably leads to lower rate of exacerbation per patient/year WMD of compared with placebo (moderate certainty).
1 finding from 1 review
HRQoL: total score · Adults (aged 40 or over) with COPD presenting with 1 or more exacerbations in the previous year. The 2 larger studies (Albert 2011; Sethi…
1 finding from 1 review
All‐cause mortality WMD of · Adults (aged 40 or over) with COPD presenting with 1 or more exacerbations in the previous year. The 2 larger studies (Albert 2011; Sethi…
Antibiotics showed no clear difference in all‐cause mortality WMD of compared with placebo (moderate certainty).
1 finding from 1 review
Serious adverse events WMD of · Adults (aged 40 or over) with COPD presenting with 1 or more exacerbations in the previous year. The 2 larger studies (Albert 2011; Sethi…
Antibiotics showed no clear difference in serious adverse events WMD of compared with placebo (moderate certainty).
1 finding from 1 review
Any adverse event WMD of · Adults (aged 40 or over) with COPD presenting with 1 or more exacerbations in the previous year. The 2 larger studies (Albert 2011; Sethi…
Antibiotics showed no clear difference in any adverse event WMD of compared with placebo (moderate certainty).
1 finding from 1 review