Sore throat · patients with sore throat
Antibiotics probably leads to lower sore throat: day 3 compared with control (moderate certainty).
2 findings from 1 review
Fever · patients with sore throat
Antibiotics showed no clear difference in fever: day 3 compared with control (high certainty).
1 finding from 1 review
Headache · patients with sore throat
Antibiotics leads to lower headache: day 3 compared with control (high certainty).
1 finding from 1 review
Rheumatic fever · patients with sore throat
Antibiotics probably leads to lower rheumatic fever (within 2 months, clinical diagnosis) compared with control (moderate certainty).
1 finding from 1 review
Glomerulonephritis · patients with sore throat
Antibiotics showed no clear difference in glomerulonephritis (within 1 month, clinical diagnosis) compared with control (low certainty).
1 finding from 1 review
Quinsy · patients with sore throat
Antibiotics leads to lower quinsy (within 2 months, clinical diagnosis) compared with control (high certainty).
1 finding from 1 review
Otitis media · patients with sore throat
Antibiotics leads to lower otitis media (within 14 days, clinical diagnosis) compared with control (high certainty).
1 finding from 1 review
Cure in adults with clinically diagnosed acute rhinosinusitis · acute rhinosinusitis in adults, whether clinically diagnosed or confirmed by imaging
Antibiotics leads to higher cure in adults with clinically diagnosed acute rhinosinusitis compared with placebo (high certainty).
1 finding from 1 review
Cure in adults with acute rhinosinusitis confirmed by radiography1 · acute rhinosinusitis in adults, whether clinically diagnosed or confirmed by imaging
Antibiotics probably leads to higher cure in adults with acute rhinosinusitis confirmed by radiography1 compared with placebo (moderate certainty).
1 finding from 1 review
Cure in adults with acute rhinosinusitis confirmed by computed tomography1,4 · acute rhinosinusitis in adults, whether clinically diagnosed or confirmed by imaging
Antibiotics probably leads to higher cure in adults with acute rhinosinusitis confirmed by computed… compared with placebo (moderate certainty).
1 finding from 1 review
Resolution of purulent secretion · acute rhinosinusitis in adults, whether clinically diagnosed or confirmed by imaging
Antibiotics leads to higher severity or duration of different clinical symptoms: resolution of… compared with placebo (high certainty).
1 finding from 1 review
Side effects – overall · acute rhinosinusitis in adults, whether clinically diagnosed or confirmed by imaging
Antibiotics leads to higher side effects: total compared with placebo (high certainty).
1 finding from 1 review
Interventions side effects: diarrhoea · acute rhinosinusitis in adults, whether clinically diagnosed or confirmed by imaging
Antibiotics leads to higher side effects: diarrhoea compared with placebo (high certainty).
1 finding from 1 review
Clinical failure · acute rhinosinusitis in adults, whether clinically diagnosed or confirmed by imaging
Antibiotics leads to lower clinical failure compared with placebo (high certainty).
1 finding from 1 review
Clinical failure rate · patients with uncomplicated acute maxillary sinusitis
Antibiotics probably leads to lower clinical failure rate compared with placebo (moderate certainty).
2 findings from 1 review
Quality of life and activity impairment · patients with uncomplicated acute maxillary sinusitis
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
All‐cause mortality · hospital‐acquired pneumonia
Should short‐course antibiotic therapy showed no clear difference in mortality compared with prolonged‐course antibiotic therapy be used (moderate certainty).
1 finding from 1 review
Mortality NF‐GNB · hospital‐acquired pneumonia
Should short‐course antibiotic therapy showed no clear difference in mortality NF‐GNB compared with prolonged‐course antibiotic therapy be used (low certainty).
1 finding from 1 review
Mortality MRSA · hospital‐acquired pneumonia
Should short‐course antibiotic therapy showed no clear difference in mortality MRSA compared with prolonged‐course antibiotic therapy be used (moderate certainty).
1 finding from 1 review
Recurrence of pneumonia · hospital‐acquired pneumonia
Should short‐course antibiotic therapy showed no clear difference in recurrence of pneumonia Clinical and/or microbiological criteria compared with prolonged‐course antibiotic therapy be used (low certainty).
1 finding from 1 review