Target lesion revascularization · people with peripheral arterial disease of the lower limbs
Drug‐eluting balloon may leads to lower target lesion revascularization compared with uncoated balloon angioplasty at 12 months (low certainty).
1 finding from 1 review
Binary restenosis · people with peripheral arterial disease of the lower limbs
Drug‐eluting balloon probably leads to lower binary restenosis compared with uncoated balloon angioplasty at 12 months (moderate certainty).
1 finding from 1 review
Death · people with peripheral arterial disease of the lower limbs
Drug‐eluting balloon showed no clear difference in death compared with uncoated balloon angioplasty at 12 months (high certainty).
1 finding from 1 review
Change in Rutherford category · people with peripheral arterial disease of the lower limbs
1 finding from 1 review
Change in ankle‐brachial index · people with peripheral arterial disease of the lower limbs
1 finding from 1 review
Primary patency ( · people with PAD
It is very uncertain whether atherectomy changes primary patency ( compared with balloon angioplasty (very low certainty).
2 findings from 1 review
Mortality ( · people with PAD
It is very uncertain whether atherectomy changes mortality ( compared with balloon angioplasty with primary stenting (very low certainty).
1 finding from 1 review
Cardiovascular events · people with PAD
It is very uncertain whether atherectomy changes fatal and non‐fatal cardiovascular events ( compared with balloon angioplasty with primary stenting (very low certainty).
1 finding from 1 review
TVR ( · people with PAD
It is very uncertain whether atherectomy changes TVR ( compared with balloon angioplasty with primary stenting (very low certainty).
2 findings from 1 review
Complication rates ( · people with PAD
It is very uncertain whether atherectomy changes complication rates ( compared with balloon angioplasty with primary stenting (very low certainty).
1 finding from 1 review
Mortality ( · people with PAD
It is very uncertain whether atherectomy changes mortality ( compared with balloon angioplasty (very low certainty).
1 finding from 1 review
Cardiovascular events · people with PAD
1 finding from 1 review
TVR ( · people with PAD
It is very uncertain whether atherectomy changes TVR ( compared with balloon angioplasty (very low certainty).
2 findings from 1 review
Complication rates ( · people with PAD
It is very uncertain whether atherectomy changes complication rates ( compared with balloon angioplasty (very low certainty).
1 finding from 1 review
Primary patency ( · people with PAD
The review found no eligible studies for this question.
2 findings from 1 review
no estimate extracted
Studies not reported
No studies found
no estimate extracted
Studies not reported
No studies found
Technical success · people with infrapopliteal arterial lesions in chronic limb‐threatening ischaemia
PTA probably leads to higher technical success ITT No. of limbs: 476 (5 RCTs) compared with stent (moderate certainty).
2 findings from 1 review
OR 3 [1.14, 7.93]
Studies not reported
Moderate
OR 2.78 [1.04, 7.41]
Studies not reported
Moderate
Procedural complications · people with infrapopliteal arterial lesions in chronic limb‐threatening ischaemia
PTA showed no clear difference in procedural complications ITT No. of participants: 360 (5 RCTs) compared with stent (moderate certainty).
2 findings from 1 review
OR 0.87 [0.01, 53.6]
Studies not reported
Moderate
OR 0.84 [0.01, 47.7]
Studies not reported
Moderate
Primary patency ( · people with infrapopliteal arterial lesions in chronic limb‐threatening ischaemia
PTA showed no clear difference in primary patency < 6 months ITT No. of lesions: 456 (3 RCTs) compared with stent (moderate certainty).
2 findings from 1 review
OR 0.88 [0.37, 2.11]
Studies not reported
Moderate
OR 0.97 [0.32, 3]
Studies not reported
Moderate
Mortality TA No. of participants: 487 (6 RCTs) · people with infrapopliteal arterial lesions in chronic limb‐threatening ischaemia
PTA showed no clear difference in mortality TA No. of participants: 487 (6 RCTs) compared with stent (moderate certainty).
1 finding from 1 review
OR 0.7 [0.42, 1.15]
Studies not reported
Moderate
Technical success · 52 people with TASC‐II D superficial femoral artery chronic total occlusions
OUTBACK re‐entry catheter showed no clear difference in technical success rate compared with manual re‐entry (low certainty).
1 finding from 1 review