Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

101 questions · 107 findings · 14 reviews · Eyes and Vision

No studies found 32 · 29.9%GRADE not reported 5 · 4.7%Very low 28 · 26.2%Low 29 · 27.1%Moderate 10 · 9.3%High 3 · 2.8%

Wavefront procedures vs conventional procedures

Proportion of eyes with uncorrected visual acuity (UCVA) of 20/20 or better post‐treatment. ‐ 12 months · Adults with refractive errors

Wavefront procedures showed no clear difference in proportion of eyes with uncorrected visual acuity (UCVA) of 20/20 or… compared with conventional procedures (low certainty).

1 finding from 1 review

Wavefront‐optimized procedures vs wavefront‐guided procedures

Eyes within ± 0.5 D of target refraction · Adults with refractive errors

Wavefront‐optimized procedures showed no clear difference in proportion of eyes within ± 0.50 diopters (D) of target refraction… compared with wavefront‐guided procedures (low certainty).

1 finding from 1 review

Wavefront‐guided LASIK vs wavefront‐guided PRK

Proportion of eyes with uncorrected visual acuity (UCVA) of 20/20 or better post‐treatment. ‐ 12 months · Adults with refractive errors

It is very uncertain whether wavefront‐guided LASIK changes proportion of eyes with uncorrected visual acuity (UCVA) of 20/20 or… compared with wavefront‐guided PRK (very low certainty).

1 finding from 1 review

Wavefront‐guided LASIK vs wavefront‐guided PRK

Loss of 1 or more lines of BSCVA at 12 months post treatment · Adults with refractive errors

It is very uncertain whether wavefront‐guided LASIK changes proportion of eyes that had lost 1 or more lines of best… compared with wavefront‐guided PRK (very low certainty).

1 finding from 1 review

Wavefront‐guided LASIK vs wavefront‐guided PRK

Eyes within ± 0.5 D of target refraction · Adults with refractive errors

It is very uncertain whether wavefront‐guided LASIK changes proportion of eyes within ± 0.50 diopters (D) of target refraction… compared with wavefront‐guided PRK (very low certainty).

1 finding from 1 review

Wavefront procedures vs conventional procedures

Proportion of eyes that had lost 1 or more lines of best spectacle‐corrected visual acuity (BSCVA) posttreatment:12 months ‐ Procedure PRK · Adults with refractive errors

Wavefront procedures showed no clear difference in proportion of eyes that had lost 1 or more lines of best… compared with conventional procedures (low certainty).

1 finding from 1 review

Wavefront procedures vs conventional procedures

Proportion of eyes within ± 0.50 diopters (D) of target refraction: 12 months ‐ Procedure PRK · Adults with refractive errors

Wavefront procedures showed no clear difference in proportion of eyes within ± 0.50 diopters (D) of target refraction:… compared with conventional procedures (low certainty).

1 finding from 1 review

Wavefront procedures vs conventional procedures

Proportion of eyes that had lost 1 or more lines of best spectacle‐corrected visual acuity (BSCVA) posttreatment‐procedure LASIK; Mean higher‐order aberrations (HOAs) post‐treatment, measured by machine with wavefront sensor; proportion of eyes wi... · Adults with refractive errors

The review found no eligible studies for this question.

1 finding from 1 review

Wavefront‐optimized procedures vs wavefront‐guided procedures

Proportion of eyes with uncorrected visual acuity (UCVA) of 20/20 or better post‐treatment. ‐ 12 months · Adults with refractive errors

Wavefront‐optimized procedures showed no clear difference in proportion of eyes with uncorrected visual acuity (UCVA) of 20/20 or… compared with wavefront‐guided procedures (low certainty).

1 finding from 1 review

Wavefront‐optimized procedures vs wavefront‐guided procedures

Loss of 1 or more lines of BSCVA at 12 months post treatment · Adults with refractive errors

Wavefront‐optimized procedures showed no clear difference in proportion of eyes that had lost 1 or more lines of best… compared with wavefront‐guided procedures (low certainty).

1 finding from 1 review

Laser‐assisted in‐situ keratomileusis (LASIK) vs photorefractive keratectomy (PRK)

Proportion of eyes with uncorrected visual acuity (UCVA) of 20/20 or better post‐treatment. ‐ 12 months · patients with myopia

Laser‐assisted in‐situ keratomileusis (LASIK) may leads to higher UCVA of 20/20 or better compared with photorefractive keratectomy (PRK) (low certainty).

1 finding from 1 review

Laser‐assisted in‐situ keratomileusis (LASIK) vs photorefractive keratectomy (PRK)

Eyes within ± 0.5 D of target refraction · patients with myopia

Laser‐assisted in‐situ keratomileusis (LASIK) showed no clear difference in within 0.50 D of target refraction compared with photorefractive keratectomy (PRK) (low certainty).

1 finding from 1 review