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What do systematic reviews say?

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Evidence found and GRADE certainty

25 questions · 25 findings · 7 reviews · Common Mental Disorders

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No studies found 3 · 12%GRADE not reported 1 · 4%Very low 8 · 32%Low 10 · 40%Moderate 3 · 12%High 0 · 0%

Trauma‐focused psychological intervention vs psychological interventions

Treatment completers · Individuals with post‐traumatic stress disorder and comorbid substance use disorder

Trauma‐focused psychological intervention showed no clear difference in treatment completers compared with active psychological intervention (low certainty).

1 finding from 1 review

CBT vs active control

Remission of anxiety diagnoses (ITT analysis) i.e. no longer meeting criteria for DSM or ICD anxiety diagnosis at the end of the trial. · children and adolescents with anxiety disorders

CBT showed no clear difference in remission of anxiety diagnoses (ITT) analysis i.e. no longer meeting… compared with active controls (moderate certainty).

1 finding from 1 review