Findings

What do systematic reviews say?

4,756 questions · 13,493 findings · 1,305 reviews · Headline outcomes only

Sort:Best matchNewest Highest certainty Download CSV

No studies found 2,594 · 19.2%GRADE not reported 728 · 5.4%Very low 2,868 · 21.3%Low 3,777 · 28%Moderate 2,620 · 19.4%High 906 · 6.7%

Ranked among the 5,000 newest matching findings; add words or filters to narrow the search.

Antibiotics vs no treatment or placebo on top of topical antiseptics

Hearing · schoolchildren with CSOM

1 finding from 1 review

Systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 204 participants
Very low

Antibiotics vs no treatment or placebo on top of topical antiseptics

Serious complications · schoolchildren with CSOM

The review found no eligible studies for this question.

1 finding from 1 review

Systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antibiotics vs no treatment or placebo on top of topical antiseptics

Suspected ototoxicity · schoolchildren with CSOM

1 finding from 1 review

Systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 204 participants
Very low

Antibiotics vs no treatment/placebo

Health‐related quality of life · children with CSOM

The review found no eligible studies for this question.

1 finding from 1 review

Systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antibiotics vs no treatment/placebo

Ear pain (otalgia) or discomfort or local irritation · children with CSOM

The review found no eligible studies for this question.

1 finding from 1 review

Systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antibiotics vs no treatment/placebo

Hearing · children with CSOM

1 finding from 1 review

Systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 33 participants
Very low

Antibiotics vs no treatment/placebo

Serious complications ‐ during 6 months of · children with CSOM

1 finding from 1 review

Systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 33 participants
Very low

Antibiotics vs no treatment/placebo

Suspected ototoxicity · children with CSOM

The review found no eligible studies for this question.

1 finding from 1 review

Systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antibiotics vs no treatment or placebo on top of topical antibiotics

Resolution of ear discharge ‐ measured at 1 to 2 weeks · people (of any age) with CSOM

Systemic antibiotics showed no clear difference in resolution of ear discharge ‐ measured at 1 to 2 weeks compared with no treatment or placebo on top of topical antibiotics (low certainty).

1 finding from 1 review

Systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
RR 1.02 [0.93, 1.12]
5 studies · 390 participants
Low

Antibiotics vs no treatment or placebo on top of topical antibiotics

Resolution of ear discharge ‐ measured after 4 weeks · people (of any age) with CSOM

The review found no eligible studies for this question.

1 finding from 1 review

Systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings ‐ AZLI vs placebo

FEV1 % predicted: relative change from baseline · adults and children with CF

1 finding from 1 review

Antibiotic therapy for chronic infection with Burkholderia cepacia complex in people with cystic fibrosis 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 99 participants
Moderate

Summary of findings ‐ AZLI vs placebo

Time to next exacerbation · adults and children with CF

1 finding from 1 review

Antibiotic therapy for chronic infection with Burkholderia cepacia complex in people with cystic fibrosis 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 100 participants
Moderate

Summary of findings ‐ AZLI vs placebo

Participants hospitalised for respiratory exacerbation · adults and children with CF

Summary of findings ‐ AZLI showed no clear difference in participants hospitalised for respiratory exacerbation compared with placebo (moderate certainty).

1 finding from 1 review

Antibiotic therapy for chronic infection with Burkholderia cepacia complex in people with cystic fibrosis 2021 · Cochrane Headline outcomes only
RR 0.88 [0.53, 1.45]
1 study · 100 participants
Moderate

Summary of findings ‐ AZLI vs placebo

Adverse events (AEs) (1 or more events) · adults and children with CF

Summary of findings ‐ AZLI showed no clear difference in any AEs compared with placebo (moderate certainty).

1 finding from 1 review

Antibiotic therapy for chronic infection with Burkholderia cepacia complex in people with cystic fibrosis 2021 · Cochrane Headline outcomes only
RR 1.08 [0.98, 1.19]
1 study · 100 participants
Moderate

Summary of findings ‐ AZLI vs placebo

All‐cause mortality · adults and children with CF

Summary of findings ‐ AZLI showed no clear difference in mortality compared with placebo (moderate certainty).

1 finding from 1 review

Antibiotic therapy for chronic infection with Burkholderia cepacia complex in people with cystic fibrosis 2021 · Cochrane Headline outcomes only
RR 5.41 [0.27, 109.87]
1 study · 100 participants
Moderate

Induced hypertension vs placebo or no intervention

Death from all causes (primary outcome) · people with acute subarachnoid haemorrhage

It is very uncertain whether induced hypertension changes death from all causes (primary outcome) compared with placebo or no intervention (very low certainty).

1 finding from 1 review

Interventions for altering blood pressure in people with acute subarachnoid haemorrhage 2021 · Cochrane Headline outcomes only
RR 1.6 [0.57, 4.42]
2 studies · 61 participants
Very low

Lowered blood pressure vs placebo

Proportion of participants with ≥ 1 serious adverse events · people with acute subarachnoid haemorrhage

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for altering blood pressure in people with acute subarachnoid haemorrhage 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Lowered blood pressure vs placebo

Quality of life · people with acute subarachnoid haemorrhage

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for altering blood pressure in people with acute subarachnoid haemorrhage 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Lowered blood pressure vs placebo

Rebleeding · people with acute subarachnoid haemorrhage

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for altering blood pressure in people with acute subarachnoid haemorrhage 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Lowered blood pressure vs placebo

Delayed cerebral ischaemia · people with acute subarachnoid haemorrhage

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for altering blood pressure in people with acute subarachnoid haemorrhage 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found