Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,783 questions · 10,022 findings · 882 reviews

No studies found 2,100 · 21%GRADE not reported 1,013 · 10.1%Very low 2,237 · 22.3%Low 2,514 · 25.1%Moderate 1,709 · 17.1%High 449 · 4.5%

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Pazopanib plus lapatinib vs lapatinib

Specific adverse events: gastrointestinal perforations or fistulae · women with persistent, recurrent, or metastatic cervical cancer

It is very uncertain whether pazopanib plus lapatinib changes specific adverse events: gastrointestinal perforations or fistulae compared with lapatinib (very low certainty).

1 finding from 1 review

Pazopanib plus lapatinib vs lapatinib

Specific adverse events: haemorrhage · women with persistent, recurrent, or metastatic cervical cancer

It is very uncertain whether pazopanib plus lapatinib changes specific adverse events: haemorrhage compared with lapatinib (very low certainty).

1 finding from 1 review

Pazopanib plus lapatinib vs lapatinib

Adverse events: thromboembolic events · women with persistent, recurrent, or metastatic cervical cancer

It is very uncertain whether pazopanib plus lapatinib changes specific adverse events: thromboembolic events compared with lapatinib (very low certainty).

1 finding from 1 review

Pazopanib vs lapatinib

Specific adverse events: gastrointestinal perforations or fistulae · women with persistent, recurrent, or metastatic cervical cancer

It is very uncertain whether pazopanib changes specific adverse events: gastrointestinal perforations or fistulae compared with lapatinib (very low certainty).

1 finding from 1 review