Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,752 questions · 6,648 findings · 688 reviews

No studies found 1,125 · 16.9%GRADE not reported 670 · 10.1%Very low 1,796 · 27%Low 1,685 · 25.3%Moderate 1,075 · 16.2%High 297 · 4.5%

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Estimates of effects, ranking, and certainty of evidence for different treatment options vs placebo

Interferon (1 RCT; 66 participants)

It is very uncertain whether estimates of effects, ranking, and certainty of evidence for… changes interferon (1 RCT; 66 participants) compared with placebo (very low certainty).

4 findings from 1 review
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Estimates of effects, ranking, and certainty of evidence for different treatment options vs placebo

Sunitinib (1 RCT; 171 participants)

Estimates of effects, ranking, and certainty of evidence for… probably leads to lower sunitinib (1 RCT; 171 participants) compared with placebo (moderate certainty).

2 findings from 1 review

Estimates of effects, ranking, and certainty of evidence for different treatment options vs placebo

Everolimus + bevacizumab + SSA (1 RCT; 150 participants)

It is very uncertain whether estimates of effects, ranking, and certainty of evidence for… changes everolimus + bevacizumab + SSA (1 RCT; 150 participants) compared with placebo (very low certainty).

1 finding from 1 review

Estimates of effects, ranking, and certainty of evidence for different treatment options vs placebo

Surufatinib (1 RCT; 172 participants)

Estimates of effects, ranking, and certainty of evidence for… leads to lower surufatinib (1 RCT; 172 participants) compared with placebo (high certainty).

2 findings from 1 review

Estimates of effects, ranking, and certainty of evidence for different treatment options vs placebo

SSA (3 RCTs; 586 participants)

Estimates of effects, ranking, and certainty of evidence for… probably leads to lower SSA (3 RCTs; 586 participants) compared with placebo (moderate certainty).

4 findings from 1 review
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Estimates of effects, ranking, and certainty of evidence for different treatment options vs placebo

Placebo (4 RCT; 789 participants)
4 findings from 1 review
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Estimates of effects, ranking, and certainty of evidence for different treatment options vs placebo

177‐Lu‐DOTATATE + SSA (1 RCT; 229 participants)

It is very uncertain whether estimates of effects, ranking, and certainty of evidence for… changes 177‐Lu‐DOTATATE + SSA (1 RCT; 229 participants) compared with placebo (very low certainty).

2 findings from 1 review

Estimates of effects, ranking, and certainty of evidence for different treatment options vs placebo

Surufatinib (1 RCT; 198 participants)

Estimates of effects, ranking, and certainty of evidence for… probably leads to higher surufatinib (1 RCT; 198 participants) compared with placebo (moderate certainty).

2 findings from 1 review

Estimates of effects, ranking, and certainty of evidence for different treatment options vs placebo

Streptozocin + 5‐FU (1 RCT; 20 participants)

It is very uncertain whether estimates of effects, ranking, and certainty of evidence for… changes streptozocin + 5‐FU (1 RCT; 20 participants) compared with placebo (very low certainty).

1 finding from 1 review