Question · asked by 1 review

Estimates of effects, ranking, and certainty of evidence for different treatment options vs placebo: SSA (3 RCTs; 586 participants)

Estimates of effects, ranking, and certainty of evidence for… probably leads to lower SSA (3 RCTs; 586 participants) compared with placebo (moderate certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Estimates of effects, ranking, and certainty of evidence for different treatment options vs placebo
SSA (3 RCTs; 586 participants)
Estimates of effects, ranking, and certainty of evidence for… probably leads to lower SSA (3 RCTs; 586 participants) compared with placebo (moderate certainty).
Treatment for gastrointestinal and pancreatic neuroendocrine tumours: a network meta‐analysis (2021) · Cochrane Headline outcomes only
HR 0.51 [0.34, 0.77]3 studies · 586 participantsModerate
Estimates of effects, ranking, and certainty of evidence for different treatment options vs placebo
SSA (7 RCTs; 796 participants)
Estimates of effects, ranking, and certainty of evidence for… probably leads to higher SSA (7 RCTs; 796 participants) compared with placebo (moderate certainty).
Treatment for gastrointestinal and pancreatic neuroendocrine tumours: a network meta‐analysis (2021) · Cochrane Headline outcomes only
OR 2.93 [1.36, 6.32]7 studies · 796 participantsModerate
Estimates of effects, ranking, and certainty of evidence for different treatment options vs placebo
SSA (5 RCTs; 492 participants)
Estimates of effects, ranking, and certainty of evidence for… leads to lower SSA (5 RCTs; 492 participants) compared with placebo (high certainty).
Treatment for gastrointestinal and pancreatic neuroendocrine tumours: a network meta‐analysis (2021) · Cochrane Headline outcomes only
HR 0.34 [0.16, 0.76]5 studies · 492 participantsHigh
Estimates of effects, ranking, and certainty of evidence for different treatment options vs placebo
SSA (4 RCTs, 804 participants)
Estimates of effects, ranking, and certainty of evidence for… probably leads to higher SSA (4 RCTs, 804 participants) compared with placebo (moderate certainty).
Treatment for gastrointestinal and pancreatic neuroendocrine tumours: a network meta‐analysis (2021) · Cochrane Headline outcomes only
OR 2.36 [1.43, 3.88]4 studies · 804 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Treatment for gastrointestinal and pancreatic neuroendocrine tumours: a network meta‐analysis
2021 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.