Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,730 questions · 18,059 findings · 1,282 reviews

No studies found 4,360 · 24.1%GRADE not reported 2,529 · 14%Very low 4,641 · 25.7%Low 4,007 · 22.2%Moderate 2,057 · 11.4%High 465 · 2.6%

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Systemic antibiotics plus antibiotic lock solutions plus tissue plasminogen activator vs systemic antibiotics plus antibiotic lock solutions plus heparin

Cure: short‐term success · patients on maintenance HD with CRBSI

It is very uncertain whether systemic antibiotics plus antibiotic lock solutions plus tissue… changes cure: short‐term success compared with systemic antibiotics plus antibiotic lock solutions plus heparin (very low certainty).

1 finding from 1 review

Catheter guidewire exchange vs catheter removal and replacement

Cure: infection‐free survival · patients on maintenance HD with CRBSI

It is very uncertain whether catheter guidewire exchange changes cure: infection‐free survival compared with catheter removal and replacement (very low certainty).

1 finding from 1 review

Systemic antibiotics plus antibiotic lock solutions plus tissue plasminogen activator vs systemic antibiotics plus antibiotic lock solutions plus heparin

Cure: long‐term success · patients on maintenance HD with CRBSI

It is very uncertain whether systemic antibiotics plus antibiotic lock solutions plus tissue… changes cure: long‐term success compared with systemic antibiotics plus antibiotic lock solutions plus heparin (very low certainty).

1 finding from 1 review

Systemic antibiotics plus antibiotic lock solutions plus tissue plasminogen activator vs systemic antibiotics plus antibiotic lock solutions plus heparin

Stenosis or thrombosis of vascular access site after catheter removal · patients on maintenance HD with CRBSI

The review found no eligible studies for this question.

1 finding from 1 review

Systemic antibiotics plus antibiotic lock solutions plus tissue plasminogen activator vs systemic antibiotics plus antibiotic lock solutions plus heparin

Development of antibiotic resistance · patients on maintenance HD with CRBSI

The review found no eligible studies for this question.

1 finding from 1 review

Systemic antibiotics alone vs systematic antibiotics plus antibiotic lock solution

Cure: successful eradication of the infection · patients on maintenance HD with CRBSI

It is very uncertain whether systemic antibiotics alone changes cure: successful eradication of the infection compared with systematic antibiotics plus antibiotic lock solution (very low certainty).

1 finding from 1 review