Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,667 questions · 21,760 findings · 2,177 reviews

No studies found 4,173 · 19.2%GRADE not reported 2,300 · 10.6%Very low 5,276 · 24.2%Low 5,764 · 26.5%Moderate 3,298 · 15.2%High 949 · 4.4%

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IPC plus pharmacological prophylaxis vs pharmacological prophylaxis alone

Incidence of DVTc (early postoperative period) · people undergoing surgery or at risk of developing VTE because of surgery, trauma or ICU stay

IPC plus pharmacological prophylaxis leads to lower incidence of DVTc (early postoperative period) compared with pharmacological prophylaxis alone (high certainty).

1 finding from 1 review

IPC plus pharmacological prophylaxis vs pharmacological prophylaxis alone

Incidence of bleedingd (early postoperative period) · people undergoing surgery or at risk of developing VTE because of surgery, trauma or ICU stay

It is very uncertain whether IPC plus pharmacological prophylaxis changes incidence of bleedinge (early postoperative period) compared with pharmacological prophylaxis alone (very low certainty).

1 finding from 1 review

IPC plus pharmacological prophylaxis vs pharmacological prophylaxis alone

Incidence of major bleedingg (early postoperative period) · people undergoing surgery or at risk of developing VTE because of surgery, trauma or ICU stay

It is very uncertain whether IPC plus pharmacological prophylaxis changes incidence of major bleedingg (early postoperative period) compared with pharmacological prophylaxis alone (very low certainty).

1 finding from 1 review

Low molecular weight heparin vs no prophylaxis

All adverse effects, including allergies at injection site, minor and major bleeding, others ( · adults undergoing KA

Low‐molecular‐weight heparin showed no clear difference in all adverse effects, including allergies at injection site, minor… compared with no prophylaxis (moderate certainty).

1 finding from 1 review

Intervention not reported

Proportion of participants who had died or become dependent at the end of the scheduled · patients with stroke

The intervention showed no clear difference in proportion of participants who had died or become dependent at the… (moderate certainty).

1 finding from 1 review

Homeopathic medicinal products (non‐individualised treatment) vs placebo or usual care

Adverse events · children aged up to 16 years with ARTIs

It is very uncertain whether homeopathic medicinal products (non‐individualised treatment) changes adverse events compared with placebo or usual care (very low certainty).

1 finding from 1 review