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What do systematic reviews say?

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Evidence found and GRADE certainty

4,315 questions · 23,557 findings · 2,311 reviews

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No studies found 4,183 · 17.8%GRADE not reported 3,930 · 16.7%Very low 5,371 · 22.8%Low 5,787 · 24.6%Moderate 3,320 · 14.1%High 966 · 4.1%

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Summary of findings table ‐ Service system approaches vs inactive control (usual care care, attention control, waitlist)

Parenting skills; postintervention · for parents who are experiencing CPTSD symptoms or have experienced maltreatment in their childhood

The review found no eligible studies for this question.

1 finding from 1 review

Parenting interventions vs inactive control (usual care care, attention control, waitlist)

Substance use ‐ post‐intervention ‐ not reported · for parents who are experiencing CPTSD symptoms or have experienced maltreatment in their childhood

The review found no eligible studies for this question.

1 finding from 1 review

Parenting interventions vs inactive control (usual care care, attention control, waitlist)

Parent relationship quality ‐ not reported · for parents who are experiencing CPTSD symptoms or have experienced maltreatment in their childhood

The review found no eligible studies for this question.

1 finding from 1 review

Parenting interventions vs inactive control (usual care care, attention control, waitlist)

Parental self‐harm ‐ post‐intervention ‐ not reported · for parents who are experiencing CPTSD symptoms or have experienced maltreatment in their childhood

The review found no eligible studies for this question.

1 finding from 1 review

Summary of findings table ‐ Psychological interventions vs inactive control (usual care care, attention control, waitlist)

Trauma‐related symptoms ‐ post‐interventionb · for parents who are experiencing CPTSD symptoms or have experienced maltreatment in their childhood
1 finding from 1 review

Summary of findings table ‐ Psychological interventions vs inactive control (usual care care, attention control, waitlist)

Psychological wellbeing ‐ post‐interventiond · for parents who are experiencing CPTSD symptoms or have experienced maltreatment in their childhood
1 finding from 1 review

Intervention not reported

All‐cause mortality at day 28 · unvaccinated, non‐hospitalized people with mild symptomatic COVID‐19 (WHO scale 2 to 3) at high risk for progression to severe disease

The intervention may leads to lower all‐cause mortality at day 28 (low certainty).

1 finding from 1 review

Intervention not reported

Discontinuation of study drug due to adverse events · unvaccinated, non‐hospitalized people with mild symptomatic COVID‐19 (WHO scale 2 to 3) at high risk for progression to severe disease

The intervention probably leads to lower discontinuation of study drug due to adverse events (moderate certainty).

1 finding from 1 review

Intervention not reported

Viral clearance at 14 days · unvaccinated, non‐hospitalized people with mild symptomatic COVID‐19 (WHO scale 2 to 3) at high risk for progression to severe disease

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

All‐cause mortality at day 28 · hospitalized people with mild to moderate symptomatic COVID‐19 (WHO scale 2 to 4) with severe comorbidities

It is very uncertain whether the intervention changes all‐cause mortality at day 28 (very low certainty).

1 finding from 1 review

Intervention not reported

Participants with new need for invasive mechanical ventilation or death · hospitalized people with mild to moderate symptomatic COVID‐19 (WHO scale 2 to 4) with severe comorbidities

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Participants discharged alive. Participants should be discharged without clinical deterioration or death · hospitalized people with mild to moderate symptomatic COVID‐19 (WHO scale 2 to 4) with severe comorbidities

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Quality of life up to 28 days and longest · hospitalized people with mild to moderate symptomatic COVID‐19 (WHO scale 2 to 4) with severe comorbidities

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

SAEs during the study period · hospitalized people with mild to moderate symptomatic COVID‐19 (WHO scale 2 to 4) with severe comorbidities

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Any grade TEAE · hospitalized people with mild to moderate symptomatic COVID‐19 (WHO scale 2 to 4) with severe comorbidities

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Any grade TRAE · hospitalized people with mild to moderate symptomatic COVID‐19 (WHO scale 2 to 4) with severe comorbidities

The review found no eligible studies for this question.

1 finding from 1 review