Physician assessment of success · glabellar lines
Summary of Findings Table ‐ OnabotulinumtoxinA 20U probably leads to higher physician assessment of success compared with placebo (moderate certainty).
1 finding from 1 review
Duration of treatment effect · glabellar lines
1 finding from 1 review
Total adverse events · glabellar lines
Summary of Findings Table ‐ OnabotulinumtoxinA 20U showed no clear difference in total adverse events compared with placebo (low certainty).
1 finding from 1 review
Duration of treatment effect · glabellar lines
1 finding from 1 review
Participant assessment of success by analysing scores and scales ‐ 20 weeks (Validated tools, wrinkles and lines at maximum contraction) · glabellar lines
Summary of Findings Table ‐ AbobotulinumtoxinA 50U leads to higher participant assessment of success by analysing scores and scales ‐… compared with placebo (high certainty).
1 finding from 1 review
Major adverse events (eyelid ptosis, eyelid sensory disorder, strabismus) · glabellar lines
Summary of Findings Table ‐ AbobotulinumtoxinA 50U showed no clear difference in major adverse events (eyelid ptosis, eyelid sensory disorder,… compared with placebo (moderate certainty).
1 finding from 1 review
Physician assessment of success · glabellar lines
Summary of Findings Table ‐ AbobotulinumtoxinA 50U probably leads to higher physician assessment of success by analysing scores and scales ‐ 4… compared with placebo (moderate certainty).
1 finding from 1 review
Total adverse events · glabellar lines
Summary of Findings Table ‐ AbobotulinumtoxinA 50U may leads to higher total adverse events compared with placebo (low certainty).
1 finding from 1 review
Adequate pain relief as reported by women · women with perineal pain in the early postpartum period
NSAID may leads to higher adequate pain relief(4 hours after administration) compared with placebo (low certainty).
2 findings from 1 review
Need for additional analgesia (4 hours after administration) · women with perineal pain in the early postpartum period
NSAID probably leads to lower need for additional analgesia(4 hours after administration) compared with placebo (moderate certainty).
1 finding from 1 review
Need for additional analgesia (6 hours after administration) · women with perineal pain in the early postpartum period
It is very uncertain whether NSAID changes need for additional analgesia (6 hours after administration) compared with placebo (very low certainty).
1 finding from 1 review
Maternal drug adverse effects(4 hours after administration) · women with perineal pain in the early postpartum period
1 finding from 1 review
Maternal drug adverse effects (6 hours after administration) · women with perineal pain in the early postpartum period
NSAID showed no clear difference in maternal drug adverse effects(6 hours after administration) compared with placebo (low certainty).
1 finding from 1 review
Neonatal drug adverse effects · women with perineal pain in the early postpartum period
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Early graft thrombosis · kidney transplant recipients
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Major bleeding events: unfractionated heparin · kidney transplant recipients
Heparin showed no clear difference in major bleeding events: unfractionated heparin compared with placebo (low certainty).
1 finding from 1 review
Major bleeding events: all heparin · kidney transplant recipients
Heparin showed no clear difference in major bleeding events: all heparin compared with placebo (low certainty).
1 finding from 1 review
Readmissions to intensive care: all heparin · kidney transplant recipients
It is very uncertain whether heparin changes readmissions to intensive care: all heparin compared with placebo (very low certainty).
1 finding from 1 review
Blood transfusion requirements · kidney transplant recipients
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Graft and patient survival · kidney transplant recipients
1 finding from 1 review
no estimate extracted
Studies not reported
Very low