What do systematic reviews say?

Higher‐dose heparin vs standard‐dose heparin

Higher‐dose heparin showed no clear difference in VTE compared with standard‐dose heparin (low certainty).

• Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery 2022 · Cochrane Headline outcomes only
  RR 0.55 [0.05, 5.99]
  4 studies · 597 participants
  Low

Heparin vs pentasaccharide

• Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 198 participants
  Very low

Heparin vs pentasaccharide

• Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 198 participants
  Very low

Heparin vs pentasaccharide

• Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 198 participants
  Very low

Heparin vs pentasaccharide

Heparin showed no clear difference in DVT compared with pentasaccharide (low certainty).

• Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery 2022 · Cochrane Headline outcomes only
  RR 0.83 [0.19, 3.61]
  1 study · 175 participants
  Low

Heparin vs pentasaccharide

It is very uncertain whether heparin changes adverse events (thrombocytopenia) compared with pentasaccharide (very low certainty).

• Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery 2022 · Cochrane Headline outcomes only
  RR 0.34 [0.01, 8.25]
  1 study · 198 participants
  Very low

Heparin started before vs after the surgical procedure

Heparin started before showed no clear difference in VTE compared with after the surgical procedure (low certainty).

• Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery 2022 · Cochrane Headline outcomes only
  RR 0.11 [0.01, 2.01]
  1 study · 100 participants
  Low

Heparin started before vs after the surgical procedure

It is very uncertain whether heparin started before changes major bleeding compared with after the surgical procedure (very low certainty).

• Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery 2022 · Cochrane Headline outcomes only
  RR 3 [0.13, 71.92]
  1 study · 100 participants
  Very low

Heparin started before vs after the surgical procedure

• Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 100 participants
  Very low

Heparin started before vs after the surgical procedure

• Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 100 participants
  Very low

Heparin started before vs after the surgical procedure

The review found no eligible studies for this question.

• Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery 2022 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Higher‐dose heparin vs standard‐dose heparin

Higher‐dose heparin showed no clear difference in major bleeding compared with standard‐dose heparin (low certainty).

• Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery 2022 · Cochrane Headline outcomes only
  RR 1.19 [0.48, 2.96]
  4 studies · 597 participants
  Low

Heparin started before vs after the surgical procedure

Heparin started before showed no clear difference in DVT compared with after the surgical procedure (low certainty).

• Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery 2022 · Cochrane Headline outcomes only
  RR 0.11 [0.01, 2.01]
  1 study · 100 participants
  Low

Heparin started before vs after the surgical procedure

The review found no eligible studies for this question.

• Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery 2022 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

IPC plus pharmacological prophylaxis vs mechanical prophylaxis alone

Combined mechanical and pharmacological prophylaxis may leads to lower VTE compared with mechanical prophylaxis alone (low certainty).

• Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery 2022 · Cochrane Headline outcomes only
  RR 0.05 [0, 0.89]
  1 study · 150 participants
  Low

IPC plus pharmacological prophylaxis vs mechanical prophylaxis alone

• Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 150 participants
  Low

IPC plus pharmacological prophylaxis vs mechanical prophylaxis alone

• Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 150 participants
  Low

IPC plus pharmacological prophylaxis vs mechanical prophylaxis alone

• Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 150 participants
  Low

IPC plus pharmacological prophylaxis vs mechanical prophylaxis alone

The review found no eligible studies for this question.

• Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery 2022 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

IPC plus pharmacological prophylaxis vs mechanical prophylaxis alone

Combined mechanical and pharmacological prophylaxis may leads to lower DVT compared with mechanical prophylaxis alone (low certainty).

• Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery 2022 · Cochrane Headline outcomes only
  RR 0.05 [0, 0.89]
  1 study · 150 participants
  Low