Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,718 questions · 1,762 findings · 100 reviews · Headline outcomes only

No studies found 507 · 28.8%GRADE not reported 115 · 6.5%Very low 556 · 31.6%Low 444 · 25.2%Moderate 114 · 6.5%High 26 · 1.5%

Summary of findings table ‐ Topical capsaicin vs placebo

Risk for at least one adverse event per patient · patients with chronic kidney disease (CKD) pruritus

Summary of findings table ‐ Topical capsaicin may leads to higher risk for at least one adverse event per patient compared with placebo (low certainty).

1 finding from 1 review

Summary of findings table ‐ Rifampin/rifampicin vs placebo

Risk for at least one adverse event per patient · participants with cholestatic pruritus (CP)

It is very uncertain whether summary of findings table ‐ Rifampin/rifampicin changes risk for at least one adverse event per patient compared with placebo (very low certainty).

1 finding from 1 review